# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4705283 | B | Inhibition of N-terminal GFP tagged human DOCK5 (1212-1642 residues) expressed in HEK293T cells assessed as reduction in exchange activity incubated for 1 hr by Western blot analysis based Rac-GTP pull-down assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
2. | ALA4705284 | F | Inhibition of resorption activity of mouse peripheral blood cell-derived osteoclasts at 5-10 uM incubated for 48 hrs by Kossa-staining based assay | Mus musculus | 10 | tissue-based format | Scientific Literature | ||
3. | ALA4705286 | B | Inhibition of C-terminal 6-histidine tagged human DOCK5 (1212 to 1642 residues) expressed in Escherichia coli assessed as reduction in nucleotide exchange efficiency at 20 to 60 uM by N-methylanthraniloyl-GDP fluorescence based nucleotide exchange assay | Homo sapiens | 10 | assay format | Scientific Literature | ||
4. | ALA4705287 | B | Inhibition of C-terminal 6-histidine tagged human TRIOGEF1 (R1232 to T1550 residues) expressed in Escherichia coli assessed as reduction in nucleotide exchange efficiency at 20 to 60 uM by N-methylanthraniloyl-GDP fluorescence based nucleotide exchange assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
5. | ALA4705289 | T | Toxicity in mouse peripheral blood cell-derived osteoclasts assessed as reduction in osteoclasts number at 20 uM incubated for 48 hrs by TRAP-staining based assay | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
6. | ALA4705290 | F | Inhibition of resorption activity of mouse peripheral blood cell-derived osteoclasts at 1-20 uM incubated for 48 hrs by Kossa-staining based assay | Mus musculus | 3 | tissue-based format | Scientific Literature |