| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4722340 | F | Antagonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced intracellular calcium influx preincubated for 20 mins followed by ATP addition measured at 0.4 secs interval for 60 times by Oregon Green BAPTA-1/AM dye-based fluorescence assay | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 2. | ALA4722342 | F | Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of ATP-induced intracellular calcium influx preincubated for 20 mins followed by ATP addition measured at 0.4 secs interval for 60 times by Oregon Green BAPTA-1/AM dye-based fluorescence assay | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 3. | ALA4722343 | F | Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of ATP-induced intracellular calcium influx at 10 uM preincubated for 20 mins followed by ATP addition measured at 0.4 secs interval for 60 times by Oregon Green BAPTA-1/AM dye-based fluorescence assay relative to control | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
| 4. | ALA4722345 | F | Antagonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as inhibition of UTP-induced intracellular calcium influx at 10 to 100 uM preincubated for 20 mins followed by UTP addition measured at 0.4 secs interval for 60 times by Oregon Green BAPTA-1/AM dye-based fluorescence assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 5. | ALA4722346 | F | Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium influx at 10 to 100 uM preincubated for 20 mins followed by UDP addition measured at 0.4 secs interval for 60 times by Oregon Green BAPTA-1/AM dye-based fluorescence assay | Rattus norvegicus | 35 | cell-based format | Scientific Literature | ||
| 6. | ALA4722348 | F | Antagonist activity at human P2Y1 receptor expressed in human 1321N1 cells assessed as inhibition of ADP-induced intracellular calcium influx at 10 uM preincubated for 20 mins followed by ADP addition measured at 0.4 secs interval for 60 times by Oregon Green BAPTA-1/AM dye-based fluorescence assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 7. | ALA4722349 | B | Antagonist activity at recombinant human Gi/Go-coupled GP2Y12 receptor expressed in CHOK1 cells assessed as inhibition of 2-(Methylthio)ADP-induced inhibition of beta-arrestin recruitment at 10 uM by pathhunter assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 8. | ALA4722350 | B | Antagonist activity at recombinant human Gi/Go-coupled GP2Y14 receptor expressed in CHOK1 cells assessed as inhibition of 2-(Methylthio)ADP-induced inhibition of beta-arrestin recruitment at 10 uM by pathhunter assay | Homo sapiens | 36 | cell-based format | Scientific Literature |
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