# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4731826 | Binding | Displacement of [3H]-NLX from mouse mu opioid receptor expressed in CHO cells measured after 1.5 hrs by competitive-binding assay | Mus musculus | 4 | ALA4725485 | cell-based format | Scientific Literature | |
2. | ALA4731827 | Functional | Agonist activity at mu opioid receptor (unknown origin) by [35S]-GTPgammaS binding assay | Homo sapiens | 3 | ALA4725485 | assay format | Scientific Literature | |
3. | ALA4731828 | Functional | Agonist activity at mu opioid receptor (unknown origin) assessed as maximum efficacy by [35S]-GTPgammaS binding assay relative to DAMGO | Homo sapiens | 3 | ALA4725485 | assay format | Scientific Literature | |
4. | ALA4731829 | Functional | Antagonist activity at human mu opioid receptor expressed in CHO cells co- expressing Gqi5 assessed as decrease in DAMGO-induced intracellular calcium mobilization incubated for 15 mins followed by DAMGO addition by Fluo-AM dye based fluorescence assay | Homo sapiens | 3 | ALA4725485 | cell-based format | Scientific Literature |