# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4671747 | ADME | Inhibition of CYP2C8 (unknown origin) | Homo sapiens | 1 | ALA4665838 | single protein format | Scientific Literature | |
2. | ALA4671748 | ADME | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | ALA4665838 | single protein format | Scientific Literature | |
3. | ALA4671749 | ADME | Clearance in C57BL/6 mouse at 1 mg/kg, iv | Mus musculus | 2 | ALA4665838 | organism-based format | Scientific Literature | |
4. | ALA4671750 | ADME | Initial plasma concentration in C57BL/6 mouse at 1 mg/kg, iv | Mus musculus | 2 | ALA4665838 | organism-based format | Scientific Literature | |
5. | ALA4671751 | ADME | MRT in C57BL/6 mouse at 3 mg/kg, po | Mus musculus | 2 | ALA4665838 | organism-based format | Scientific Literature | |
6. | ALA4671752 | ADME | Terminal half life in C57BL/6 mouse at 3 mg/kg, po | Mus musculus | 2 | ALA4665838 | organism-based format | Scientific Literature | |
7. | ALA4671753 | ADME | Cmax in C57BL/6 mouse at 3 mg/kg, po | Mus musculus | 2 | ALA4665838 | organism-based format | Scientific Literature | |
8. | ALA4671754 | ADME | AUC (0 to t) in C57BL/6 mouse at 3 mg/kg, po | Mus musculus | 2 | ALA4665838 | organism-based format | Scientific Literature | |
9. | ALA4671755 | ADME | Tmax in C57BL/6 mouse at 3 mg/kg, po | Mus musculus | 2 | ALA4665838 | organism-based format | Scientific Literature | |
10. | ALA4671756 | ADME | Metabolic stability in human liver microsomes | Homo sapiens | 1 | ALA4665838 | microsome format | Scientific Literature | |
11. | ALA4671757 | ADME | Permeability in human Caco2 cells | Homo sapiens | 1 | ALA4665838 | cell-based format | Scientific Literature | |
12. | ALA4671758 | ADME | Metabolic stability in dog liver microsomes | Canis lupus familiaris | 1 | ALA4665838 | microsome format | Scientific Literature | |
13. | ALA4671759 | ADME | Metabolic stability in mouse liver microsomes | Mus musculus | 1 | ALA4665838 | microsome format | Scientific Literature | |
14. | ALA4671760 | Physicochemical | Aqueous solubility of the compound | 1 | ALA4665838 | small-molecule physicochemical format | Scientific Literature | ||
15. | ALA4671761 | Binding | Inhibition of AIM2 inflammasome (unknown origin) | Homo sapiens | 1 | ALA4665838 | single protein format | Scientific Literature | |
16. | ALA4671762 | Binding | Inhibition of NLRP3 (unknown origin) assessed as inhibition of TNFalpha production by cell based assay | Homo sapiens | 1 | ALA4665838 | cell-based format | Scientific Literature | |
17. | ALA4671763 | Binding | Inhibition of NLRP3 (unknown origin) assessed as inhibition of IL-18 production by cell based assay | Homo sapiens | 1 | ALA4665838 | cell-based format | Scientific Literature | |
18. | ALA4671764 | Binding | Inhibition of NLRP3 inflammasome activation in human THP1 cells assessed as inhibition of IL-1beta release in presence of MSU | Homo sapiens | 1 | ALA4665838 | cell-based format | Scientific Literature | |
19. | ALA4671765 | Binding | Inhibition of NLRP3 inflammasome activation in human THP1 cells assessed as inhibition of IL-1beta release in presence of nigericin | Homo sapiens | 1 | ALA4665838 | cell-based format | Scientific Literature | |
20. | ALA4671767 | Binding | Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta production | Homo sapiens | 26 | ALA4665838 | cell-based format | Scientific Literature |