# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4671747 | A | Inhibition of CYP2C8 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA4671748 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA4671749 | A | Clearance in C57BL/6 mouse at 1 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
4. | ALA4671750 | A | Initial plasma concentration in C57BL/6 mouse at 1 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
5. | ALA4671751 | A | MRT in C57BL/6 mouse at 3 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
6. | ALA4671752 | A | Terminal half life in C57BL/6 mouse at 3 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
7. | ALA4671753 | A | Cmax in C57BL/6 mouse at 3 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
8. | ALA4671754 | A | AUC (0 to t) in C57BL/6 mouse at 3 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
9. | ALA4671755 | A | Tmax in C57BL/6 mouse at 3 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
10. | ALA4671756 | A | Metabolic stability in human liver microsomes | Homo sapiens | 1 | microsome format | Scientific Literature | ||
11. | ALA4671757 | A | Permeability in human Caco2 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4671758 | A | Metabolic stability in dog liver microsomes | Canis lupus familiaris | 1 | microsome format | Scientific Literature | ||
13. | ALA4671759 | A | Metabolic stability in mouse liver microsomes | Mus musculus | 1 | microsome format | Scientific Literature | ||
14. | ALA4671760 | P | Aqueous solubility of the compound | 1 | small-molecule physicochemical format | Scientific Literature | |||
15. | ALA4671761 | B | Inhibition of AIM2 inflammasome (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
16. | ALA4671762 | B | Inhibition of NLRP3 (unknown origin) assessed as inhibition of TNFalpha production by cell based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA4671763 | B | Inhibition of NLRP3 (unknown origin) assessed as inhibition of IL-18 production by cell based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA4671764 | B | Inhibition of NLRP3 inflammasome activation in human THP1 cells assessed as inhibition of IL-1beta release in presence of MSU | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4671765 | B | Inhibition of NLRP3 inflammasome activation in human THP1 cells assessed as inhibition of IL-1beta release in presence of nigericin | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA4671767 | B | Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta production | Homo sapiens | 26 | cell-based format | Scientific Literature |