# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4731361 | F | Antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in human BE(2)-M17 cells pretreated with compound for 2 hrs followed by viral infection at MOI of 1.2 and measured after 7 hrs by immunostaining based confocal microscopic analysis | Venezuelan equine encephalitis virus | 11 | ALA4725463 | organism-based format | Scientific Literature | |
2. | ALA4731362 | T | Selectivity index, ratio of CC50 for cytotoxicity against mouse Neuro-2a cells to EC50 for antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in mouse Neuro-2a cells | 10 | ALA4725463 | cell-based format | Scientific Literature | ||
3. | ALA4731363 | F | Antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in mouse Neuro-2a cells pretreated with compound for 2 hrs followed by viral infection at MOI of 3.5 and measured after 7 hrs by immunostaining based confocal microscopic analysis | Venezuelan equine encephalitis virus | 11 | ALA4725463 | organism-based format | Scientific Literature | |
4. | ALA4731364 | F | Antiviral activity against Venezuelan equine encephalitis virus Trinidad infected in Vero cells at MOI of 0.01 after 20 hrs by immunostaining based confocal microscopic analysis | Venezuelan equine encephalitis virus | 2 | ALA4725463 | organism-based format | Scientific Literature | |
5. | ALA4731365 | F | Antiviral activity against Venezuelan equine encephalitis virus Trinidad infected in HeLa cells at MOI of 0.1 after 20 hrs by immunostaining based confocal microscopic analysis | Venezuelan equine encephalitis virus | 2 | ALA4725463 | organism-based format | Scientific Literature | |
6. | ALA4731366 | F | Antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in mouse cortical neurons at MOI of 0.04 after 20 hrs by immunostaining based confocal microscopic analysis | Venezuelan equine encephalitis virus | 3 | ALA4725463 | organism-based format | Scientific Literature | |
7. | ALA4731372 | T | Selectivity index, ratio of CC50 for cytotoxicity against human BE(2)-M17 cells to EC50 for antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in human BE(2)-M17 cells | 10 | ALA4725463 | cell-based format | Scientific Literature | ||
8. | ALA4731373 | T | Selectivity index, ratio of CC50 for cytotoxicity against african green monkey Vero cells to EC50 for antiviral activity against Venezuelan equine encephalitis virus Trinidad infected in Vero cells | 2 | ALA4725463 | cell-based format | Scientific Literature | ||
9. | ALA4731374 | T | Selectivity index, ratio of CC50 for cytotoxicity against human HeLa cells to EC50 for antiviral activity against Venezuelan equine encephalitis virus Trinidad infected in HeLa cells | 2 | ALA4725463 | cell-based format | Scientific Literature | ||
10. | ALA4731375 | T | Selectivity index, ratio of CC50 for cytotoxicity against mouse cortical neurons to EC50 for antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in mouse cortical neurons | 3 | ALA4725463 | assay format | Scientific Literature | ||
11. | ALA4731378 | A | Cytotoxicity against human SK-N-BE(2)-M17 cells | Homo sapiens | 11 | ALA4725463 | cell-based format | Scientific Literature | |
12. | ALA4731379 | A | Cytotoxicity against mouse N2a cells | Mus musculus | 10 | ALA4725463 | cell-based format | Scientific Literature | |
13. | ALA4731380 | A | Cytotoxicity against green monkey Vero cells | Chlorocebus sabaeus | 2 | ALA4725463 | cell-based format | Scientific Literature | |
14. | ALA4731381 | A | Cytotoxicity against mouse cortical neurons | Mus musculus | 3 | ALA4725463 | cell-based format | Scientific Literature |