| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4684161 | ADME | Cytotoxicity against human NHDF cells assessed as reduction in cell viability measured after 72 hrs by MTS assay | Homo sapiens | 2 | ALA4680170 | cell-based format | Scientific Literature | |
| 2. | ALA4684162 | Functional | Antiproliferative activity against human HCT 116 cells assessed as reduction in cell viability measured after 72 hrs by MTS assay | Homo sapiens | 2 | ALA4680170 | cell-based format | Scientific Literature | |
| 3. | ALA4684163 | Functional | Antiproliferative activity against human MCF-7 cells assessed as reduction in cell viability measured after 72 hrs by MTS assay | Homo sapiens | 2 | ALA4680170 | cell-based format | Scientific Literature | |
| 4. | ALA4684164 | Functional | Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTS assay | Homo sapiens | 2 | ALA4680170 | cell-based format | Scientific Literature | |
| 5. | ALA4684165 | Functional | Antiproliferative activity against human PANC-1 cells assessed as reduction in cell viability measured after 72 hrs by MTS assay | Homo sapiens | 2 | ALA4680170 | cell-based format | Scientific Literature | |
| 6. | ALA4684166 | Functional | Antiproliferative activity against human U251 cells assessed as reduction in cell viability measured after 72 hrs by MTS assay | Homo sapiens | 2 | ALA4680170 | cell-based format | Scientific Literature | |
| 7. | ALA4684167 | Functional | Induction of cell cycle arrest in human MCF-7 cells assessed as accumulation at G0/G1 phase at 1 uM incubated for 24 hrs by Muse cell analyzer based flow cytometry (Rvb = 47.4%) | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature | |
| 8. | ALA4684168 | Functional | Induction of apoptosis in human MCF-7 cells assessed as proportion of viable cells at 1 uM incubated for 48 hrs by Annexin V Muse cell analyzer based flow cytometry (Rvb = 94.2%) | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature | |
| 9. | ALA4684169 | Functional | Induction of apoptosis in human MCF-7 cells assessed as proportion of early apoptotic cells at 1 uM incubated for 48 hrs by Annexin V Muse cell analyzer based flow cytometry (Rvb = 3.05%) | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature | |
| 10. | ALA4684170 | Functional | Induction of apoptosis in human MCF-7 cells assessed as proportion of late apoptotic cells at 1 uM incubated for 48 hrs by Annexin V Muse cell analyzer based flow cytometry (Rvb = 2.3%) | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature | |
| 11. | ALA4684171 | Functional | Induction of ROS generation in human MCF7 cells at 1 uM measured after 1 hr by CellRox Green reagent/Hoechst 33342 staining based fluorescence analysis | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature | |
| 12. | ALA4684172 | Functional | Induction of apoptosis in human MCF7 cells assessed as decrease in p21 expression at 2.5 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature | |
| 13. | ALA4684173 | Functional | Antiproliferative activity against human MCF-7 cells assessed as reduction in cell viability measured after 72 hrs in presence of FeSO4 by MTS assay | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature | |
| 14. | ALA4684174 | Functional | Antiproliferative activity against human MCF-7 cells assessed as reduction in cell viability measured after 72 hrs in presence of FeCl3 by MTS assay | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature | |
| 15. | ALA4684175 | Functional | Antiproliferative activity against human MCF-7 cells assessed as reduction in cell viability measured after 72 hrs in presence of CdSO4 by MTS assay | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature | |
| 16. | ALA4684176 | Functional | Antiproliferative activity against human MCF-7 cells assessed as reduction in cell viability measured after 72 hrs in presence of ZnCl2 by MTS assay | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature | |
| 17. | ALA4684177 | Functional | Antiproliferative activity against human MCF-7 cells assessed as reduction in cell viability measured after 72 hrs in presence of CuSO4 by MTS assay | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature | |
| 18. | ALA4684178 | Functional | Induction of cell cycle arrest in human MCF-7 cells assessed as accumulation at S phase at 1 uM incubated for 24 hrs by Muse cell analyzer based flow cytometry (Rvb = 11.1%) | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature | |
| 19. | ALA4684179 | Functional | Induction of cell cycle arrest in human MCF-7 cells assessed as accumulation at G2/M phase at 1 uM incubated for 24 hrs by Muse cell analyzer based flow cytometry (Rvb = 36.9%) | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature | |
| 20. | ALA4684180 | Functional | Induction of cell cycle arrest in human MCF-7 cells assessed as accumulation at G0/G1 phase at 2.5 uM incubated for 24 hrs by Muse cell analyzer based flow cytometry (Rvb = 47.4%) | Homo sapiens | 1 | ALA4680170 | cell-based format | Scientific Literature |
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