#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4686122	Binding	Protac activity at VHL/EGFR in human A431 cells assessed as EGFR degradation by Western blot analysis	Homo sapiens	9	ALA4680227	cell-based format	Scientific Literature
2.	ALA4686126	Binding	Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as EGFR degradation by Western blot analysis	Homo sapiens	9	ALA4680227	cell-based format	Scientific Literature
3.	ALA4686127	Binding	Inhibition of EGFR L858R/T790M (unknown origin) using Poly (Glu, Tyr) 4:1 as substrate measured after 1 hr by ELISA	Homo sapiens	1	ALA4680227	single protein format	Scientific Literature
4.	ALA4686128	Binding	Inhibition of wild-type EGFR (unknown origin) using Poly (Glu, Tyr) 4:1 as substrate measured after 1 hr by ELISA	Homo sapiens	1	ALA4680227	single protein format	Scientific Literature
5.	ALA4686129	Binding	Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as EGFR degradation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
6.	ALA4686130	Binding	Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as reduction in EGFR autophosphorylation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
7.	ALA4686131	Binding	Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as reduction in AKT phosphorylation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
8.	ALA4686132	Binding	Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as reduction in ERK phosphorylation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
9.	ALA4686133	ADME	Effect on AKT level in human NCI-H1975 cells up to 10000 nM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
10.	ALA4686134	ADME	Effect on ERK level in human NCI-H1975 cells up to 10000 nM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
11.	ALA4686135	Binding	Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as EGFR degradation at >2000 nM measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
12.	ALA4686136	Binding	Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as reduction in AKT phosphorylation at >2000 nM measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
13.	ALA4686137	Binding	Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as reduction in ERK phosphorylation at >2000 nM measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
14.	ALA4686142	Binding	Protac activity at VHL/EGFR in human A431 cells assessed as EGFR degradation up to 10000 nM measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
15.	ALA4686143	Binding	Protac activity at VHL/EGFR in human A431 cells assessed as reduction in AKT phosphorylation up to 10000 nM measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
16.	ALA4686144	Binding	Protac activity at VHL/EGFR in human A431 cells assessed as reduction in ERK phosphorylation up to 10000 nM measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
17.	ALA4686145	Binding	Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation at 200 nM measured after 6 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
18.	ALA4686146	Binding	Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation at 200 nM measured after 12 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
19.	ALA4686147	Binding	Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation at 200 nM measured after 24 hrs by Western blot analysis	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature
20.	ALA4686148	Functional	Antiproliferative activity against human NCI-H1975 cells measured after 72 hrs by CCK8 assay	Homo sapiens	1	ALA4680227	cell-based format	Scientific Literature