# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4723653 | F | Cytotoxicity against human MDA-MB-231 cells | Homo sapiens | 13 | ALA4715861 | cell-based format | Scientific Literature | |
2. | ALA4723654 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 9 | ALA4715861 | single protein format | Scientific Literature | |
3. | ALA4723655 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 2 | ALA4715861 | single protein format | Scientific Literature | |
4. | ALA4723656 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 2 | ALA4715861 | single protein format | Scientific Literature | |
5. | ALA4723657 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 2 | ALA4715861 | single protein format | Scientific Literature | |
6. | ALA4723658 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 2 | ALA4715861 | single protein format | Scientific Literature | |
7. | ALA4723659 | A | Stability in human microsomes assessed as parent compound remaining at 60 mins | Homo sapiens | 2 | ALA4715861 | microsome format | Scientific Literature | |
8. | ALA4723660 | A | Stability in dog microsomes assessed as parent compound remaining at 60 mins | Canis lupus familiaris | 2 | ALA4715861 | microsome format | Scientific Literature | |
9. | ALA4723661 | A | Stability in rat microsomes assessed as parent compound remaining at 60 mins | Rattus norvegicus | 2 | ALA4715861 | microsome format | Scientific Literature | |
10. | ALA4723662 | A | Stability in mouse microsomes assessed as parent compound remaining at 60 mins | Mus musculus | 2 | ALA4715861 | microsome format | Scientific Literature | |
11. | ALA4723663 | B | Binding affinity to human XIAP-BIR3 (241 to 356 residues) | Homo sapiens | 1 | ALA4715861 | single protein format | Scientific Literature | |
12. | ALA4723664 | B | Antagonist activity at XIAP in human MDA-MB-231 cells assessed as fold change in Caspase-9 activation at 1 nM | Homo sapiens | 1 | ALA4715861 | cell-based format | Scientific Literature | |
13. | ALA4723665 | B | Antagonist activity at XIAP in human MDA-MB-231 cells assessed as fold change in Caspase-3 activation at 1 nM | Homo sapiens | 1 | ALA4715861 | cell-based format | Scientific Literature | |
14. | ALA4723666 | F | Cytotoxicity against human MDA-MB-468 cells | Homo sapiens | 1 | ALA4715861 | cell-based format | Scientific Literature | |
15. | ALA4723667 | F | Cytotoxicity against human MCF7 cells | Homo sapiens | 1 | ALA4715861 | cell-based format | Scientific Literature | |
16. | ALA4723668 | F | Cytotoxicity against human OVCAR-3 cells | Homo sapiens | 1 | ALA4715861 | cell-based format | Scientific Literature | |
17. | ALA4723669 | F | Cytotoxicity against human BxPC3 cells | Homo sapiens | 1 | ALA4715861 | cell-based format | Scientific Literature | |
18. | ALA4723670 | F | Cytotoxicity against human PANC-1 cells | Homo sapiens | 1 | ALA4715861 | cell-based format | Scientific Literature | |
19. | ALA4723671 | F | Cytotoxicity against human MIA PaCa-2 cells | Homo sapiens | 1 | ALA4715861 | cell-based format | Scientific Literature | |
20. | ALA4723672 | F | Cytotoxicity against human J82 cells | Homo sapiens | 1 | ALA4715861 | cell-based format | Scientific Literature |