# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4735367 | Binding | Binding affinity to human N-terminal His6-tagged/thrombin cleavage site fused/ AVI-tagged EED (1 to 441 residues) expressed in Escherichia coli BL21(DE3) cells by surface plasmon resonance method | Homo sapiens | 2 | ALA4732117 | cell-based format | Scientific Literature | |
2. | ALA4735368 | Functional | Antiproliferative activity against human Karpas422 cells after 14 days by celltiter-glo luminescent cell viability assay | Homo sapiens | 3 | ALA4732117 | cell-based format | Scientific Literature | |
3. | ALA4735369 | ADME | Drug concentration in cytoplasm of human G401 cells assessed per million cells at 10 uM incubated for 2 hrs by UPLC-MS analysis | Homo sapiens | 3 | ALA4732117 | subcellular format | Scientific Literature | |
4. | ALA4735370 | ADME | Drug concentration in nucleus of human G401 cells assessed per million cells at 10 uM incubated for 2 hrs by UPLC-MS analysis | Homo sapiens | 3 | ALA4732117 | subcellular format | Scientific Literature | |
5. | ALA5137713 | Binding | Binding affinity to EED (unknown origin) assessed as dissociation constant | Homo sapiens | 2 | ALA5136974 | single protein format | Scientific Literature | |
6. | ALA5137714 | Binding | Inhibition of PRC2 (unknown origin) | Homo sapiens | 2 | ALA5136974 | assay format | Scientific Literature |