| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4703097 | B | Inhibition of PMA-induced MPO in human Neutrophil incubated for 3 mins by luminometry | Homo sapiens | 3 | tissue-based format | Scientific Literature | ||
| 2. | ALA4703098 | B | Binding affinity to human neutrophil MPO delta (1-95) measured for 5 mins by SPR assay | Homo sapiens | 4 | tissue-based format | Scientific Literature | ||
| 3. | ALA4703099 | B | Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assay | Homo sapiens | 16 | single protein format | Scientific Literature | ||
| 4. | ALA4703100 | B | Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assay | Homo sapiens | 16 | single protein format | Scientific Literature | ||
| 5. | ALA4703101 | A | Inhibition of human MGMT using 06-benzylguanine as substrate incubated for 30 mins by LC/MS analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 6. | ALA4703102 | P | Stability of compound at pH 1 assessed as half life | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA4703103 | A | Metabolic stability in human liver microsomes assessed as compound remaining | Homo sapiens | 13 | microsome format | Scientific Literature | ||
| 8. | ALA4703104 | A | Metabolic stability in rat liver microsomes assessed as compound remaining | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
| 9. | ALA4703105 | A | Metabolic stability in mouse liver microsomes assessed as compound remaining | Mus musculus | 13 | microsome format | Scientific Literature | ||
| 10. | ALA4703106 | A | Permeability of compound at pH 5.5 by PAMPA assay | 2 | assay format | Scientific Literature | |||
| 11. | ALA4703107 | A | Permeability of compound at pH 7.4 by PAMPA assay | 15 | assay format | Scientific Literature | |||
| 12. | ALA4703108 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 13. | ALA4703109 | A | Inhibition of CYP2B6 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 14. | ALA4703110 | A | Inhibition of CYP2C8 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 15. | ALA4703111 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 16. | ALA4703112 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 17. | ALA4703113 | A | Cmax in CD-1 mouse at 3 mg/kg, po by LC/MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA4703114 | A | AUCtot in CD-1 mouse at 3 mg/kg, po by LC/MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA4703115 | A | Half life in CD-1 mouse at 3 mg/kg, po by LC/MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA4703116 | A | Protein binding in human plasma assessed as free fraction | Homo sapiens | 2 | cell-free format | Scientific Literature |
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