| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4705577 | B | Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential incubated for 5 mins by voltage-clamp assay | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
| 2. | ALA4705578 | B | Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential incubated for 5 mins by voltage-clamp assay | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
| 3. | ALA4705579 | B | Selectivity index, ratio of IC50 for rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes to IC50 for rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
| 4. | ALA4705581 | B | Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential incubated for 5 mins by voltage-clamp assay relative to LvIA IC50 | Rattus norvegicus | 16 | cell-based format | Scientific Literature | ||
| 5. | ALA4705600 | B | Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential incubated for 5 mins by voltage-clamp assay relative to LvIA IC50 | Rattus norvegicus | 16 | cell-based format | Scientific Literature |
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