# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4671939 | Functional | Cytotoxicity against human MDA-MB-231 cells harboring CRISPR/Cas9 assessed as reduction in cell viability at 300 nM by SRB assay | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
2. | ALA4671940 | Functional | Antiproliferative activity against human TC-32 cells assessed as reduction in cell viability after 48 hrs by SRB assay | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
3. | ALA4671941 | Functional | Antiproliferative activity against human SK-ES1 cells assessed as reduction in cell viability after 48 hrs by SRB assay | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
4. | ALA4671954 | Functional | Induction of cell cycle arret in human MDA-MB-231 cells assessed as G2/M phase accumulation at LC50 concentration after 18 hrs by Krishan's staining based cell analyzer method | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
5. | ALA4671955 | Functional | Induction of cell cycle arret in human MDA-MB-231 cells assessed as G1 phase accumulation at LC50 concentration after 18 hrs by Krishan's staining based cell analyzer method | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
6. | ALA4671956 | Functional | Induction of cell cycle arret in human MDA-MB-231 cells assessed as S phase accumulation at LC50 concentration after 18 hrs by Krishan's staining based cell analyzer method | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
7. | ALA4671957 | Binding | Inhibition of phosphorylation of P70S6K at T389 residue in human MDA-MB-231 cells at 300 nM preincubated for 6 hrs followed FBS-stimulation and measured after 0.25 to 2 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
8. | ALA4671958 | Functional | Effect on P70S6K regulation in human MDA-MB-231 cells at 300 nM preincubated for 6 hrs followed FBS-stimulation and measured after 0.25 to 2 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
9. | ALA4671959 | Binding | Inhibition of phosphorylation of Erk1/2 in human MDA-MB-231 cells at 300 nM preincubated for 6 hrs followed FBS-stimulation and measured after 0.25 to 2 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
10. | ALA4671960 | Functional | Effect on Erk1/2 regulation in human MDA-MB-231 cells at 300 nM preincubated for 6 hrs followed FBS-stimulation and measured after 0.25 to 2 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
11. | ALA4671961 | Binding | Inhibition of phosphorylation of Akt at S473 residue in human MDA-MB-231 cells at 300 nM preincubated for 6 hrs followed FBS-stimulation and measured after 0.25 to 2 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
12. | ALA4671962 | Functional | Effect on Akt regulation in human MDA-MB-231 cells at 300 nM preincubated for 6 hrs followed FBS-stimulation and measured after 0.25 to 2 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
13. | ALA4671965 | Functional | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability at 0.03 to 3 uM after 48 hrs in presence of GW9662 by SRB assay | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
14. | ALA4671966 | Functional | Cytotoxicity against human MDA-MB-453 cells assessed as reduction in cell viability at 0.03 to 3 uM after 48 hrs in presence of GW9662 by SRB assay | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
15. | ALA4671967 | Functional | Antiproliferative activity against human A673 cells assessed as reduction in cell viability after 48 hrs by SRB assay | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
16. | ALA4671968 | Functional | Cytotoxicity against CRISPR/Cas9-mediated HSD17B11 knock-out human MDA-MB-231 cells at 1 uM incubated for 2 weeks | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
17. | ALA4671969 | Functional | Cytotoxicity against HSD17B11 siRNA knock-out human MDA-MB-231 cells assessed as reduction in cell viability at 300 nM incubated for 48 hrs by SRB assay | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
18. | ALA4671970 | Functional | Ratio of TGI for cytotoxicity against HSD17B11 siRNA knock-out human MDA-MB-231 cells to TGI for cytotoxicity against human MDA-MB-231 cells | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
19. | ALA4671971 | Functional | Cytotoxicity against human BT-549 cells over expressing HSD17B11 assessed as reduction in cell viability at 1 to 10 uM by SRB assay | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature | |
20. | ALA4671972 | Functional | Antiproliferative activity against human RDES cells assessed as reduction in cell viability after 48 hrs by SRB assay | Homo sapiens | 1 | ALA4665845 | cell-based format | Scientific Literature |