| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4670518 | F | Antiviral activity against vesicular stomatitis virus assessed as inhibition of viral entry | Vesicular stomatitis virus | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA4670519 | F | Antiviral activity against Influenza A virus H5N1 assessed as inhibition of viral entry | Influenza A virus | 2 | organism-based format | Scientific Literature | ||
| 3. | ALA4670520 | F | Antiviral activity against Ebolavirus (pBDBV) assessed as inhibition of viral entry | Ebolavirus | 3 | organism-based format | Scientific Literature | ||
| 4. | ALA4670521 | F | Antiviral activity against Mengla-virus assessed as inhibition of viral entry | Mengla dianlovirus | 3 | assay format | Scientific Literature | ||
| 5. | ALA4670522 | F | Antiviral activity against Ebolavirus Tai Forest assessed as inhibition of viral entry | Ebolavirus | 3 | organism-based format | Scientific Literature | ||
| 6. | ALA4670523 | F | Antiviral activity against Ebolavirus (pRESTV) assessed as inhibition of viral entry | Ebolavirus | 3 | organism-based format | Scientific Literature | ||
| 7. | ALA4670524 | B | Agonist activity at ER-alpha in human MCF-7:WS8 cells transfected with an estrogen response element incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA4670525 | B | Antagonist activity at ER-alpha in human MCF-7:WS8 cells transfected with an estrogen response element assessed as suppression of estrogen-induced response incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA4670526 | B | Binding affinity to glycoprotein T502S mutant in pseudotyped Ebola virus - Mayinga, Zaire infected in human A549 cells at 0.12 to 250 uM assessed as reduction in viral infection incubated for 48 hrs by luciferase reporter gene assay relative to wild type | Ebola virus - Mayinga, Zaire, 1976 | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4670531 | B | Binding affinity to glycoprotein L515V mutant in pseudotyped Ebola virus - Mayinga, Zaire infected in human A549 cells at 0.12 to 250 uM assessed as reduction in viral infection incubated for 48 hrs by luciferase reporter gene assay relative to wild type | Ebola virus - Mayinga, Zaire, 1976 | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA4670532 | B | Binding affinity to glycoprotein L184M mutant in pseudotyped Ebola virus - Mayinga, Zaire infected in human A549 cells at 0.12 to 250 uM assessed as reduction in viral infection incubated for 48 hrs by luciferase reporter gene assay relative to wild type | Ebola virus - Mayinga, Zaire, 1976 | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA4670535 | A | Cytotoxicity in human A549 cells assessed as reduction in cell viability by cellTiter-Glo luminescent cell viability assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA4670536 | T | Selectivity index, ratio of CC50 for human A549 cells to IC50 for antiviral activity against pseudotyped Marburgvirus-Angola infected in human A549 cells | 18 | cell-based format | Scientific Literature | |||
| 14. | ALA4670537 | F | Antiviral activity against pseudotyped Marburgvirus-Angola infected in human A549 cells assessed as reduction in viral infection incubated for 24 hrs by Hoechst staining based fluorescence assay | Marburgvirus | 18 | organism-based format | Scientific Literature | ||
| 15. | ALA4670538 | T | Selectivity index, ratio of CC50 for human A549 cells to IC50 for antiviral activity against pseudotyped Ebola virus - Zaire (1995) Kikwit infected in human A549 cells | 18 | cell-based format | Scientific Literature | |||
| 16. | ALA4670539 | F | Antiviral activity against pseudotyped Ebola virus - Zaire (1995) Kikwit infected in human A549 cells assessed as reduction in viral infection incubated for 24 hrs by Hoechst staining based fluorescence assay | Ebola virus - Zaire (1995) | 18 | cell-based format | Scientific Literature | ||
| 17. | ALA4670540 | T | Selectivity index, ratio of CC50 for human A549 cells to IC50 for antiviral activity against pseudotyped Marburgvirus-Musoke infected in human A549 cells | 31 | cell-based format | Scientific Literature | |||
| 18. | ALA4670541 | T | Selectivity index, ratio of CC50 for human A549 cells to IC50 for antiviral activity against pseudotyped Ebola virus - Mayinga, Zaire infected in human A549 cells | 31 | cell-based format | Scientific Literature | |||
| 19. | ALA4670542 | F | Antiviral activity against pseudotyped Ebola virus - Mayinga, Zaire infected in human A549 cells assessed as reduction in viral infection incubated for 48 hrs by luciferase reporter gene assay | Zaire ebolavirus | 31 | organism-based format | Scientific Literature | ||
| 20. | ALA4670543 | F | Antiviral activity against pseudotyped Marburgvirus-Musoke infected in human A549 cells assessed as reduction in viral infection incubated for 48 hrs by luciferase reporter gene assay | Marburgvirus | 31 | organism-based format | Scientific Literature |
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