#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4739796	B	Inhibition of biotinylated-THZ1 binding to CDK12/CDK13 in human Jurkat cells assessed as reduction in cyclin K pull down at 1 uM preincubated for 6 hrs followed by biotinylated-THZ1 addition by Western blotting based pull-down assay	Homo sapiens	2	ALA4739714	cell-based format	Patent Bioactivity Data
2.	ALA4739797	B	Inhibition of biotinylated-THZ1 binding to CDK7 in human Jurkat cells assessed as reduction in cyclin H pull down at 1 uM preincubated for 6 hrs followed by biotinylated-THZ1 addition by Western blotting based pull-down assay	Homo sapiens	4	ALA4739714	cell-based format	Patent Bioactivity Data
3.	ALA4739798	B	Inhibition of biotinylated-THZ1 binding to CDK12 in human Jurkat cells assessed as reduction in cyclin K pull down at 1 uM preincubated for 6 hrs followed by biotinylated-THZ1 addition by Western blotting based pull-down assay	Homo sapiens	6	ALA4739714	cell-based format	Patent Bioactivity Data
4.	ALA4739799	F	Antiproliferative activity against human Jurkat cells measured after 72 hrs by Celltiter glo assay	Homo sapiens	8	ALA4739714	cell-based format	Patent Bioactivity Data
5.	ALA4739800	B	Inhibition of CDK2/cyclin A (unknown origin)	Homo sapiens	13	ALA4739714	protein complex format	Patent Bioactivity Data
6.	ALA4739801	B	Inhibition of CDK7/cyclin H/MNAT1 (unknown origin)	Homo sapiens	13	ALA4739714	protein complex format	Patent Bioactivity Data
7.	ALA4739802	B	Inhibition of CDK9/cyclin T1 (unknown origin)	Homo sapiens	13	ALA4739714	protein complex format	Patent Bioactivity Data
8.	ALA4739803	F	Antiproliferative activity against human HAP1 cells measured after 72 hrs by CellTiter-Glo Luminescent Cell Viability Assay	Homo sapiens	1	ALA4739714	cell-based format	Patent Bioactivity Data
9.	ALA4739804	F	Antiproliferative activity against human HAP1 cells harboring CDK12 C1039S/CDK13 C1017S double mutant measured after 72 hrs by CellTiter-Glo Luminescent Cell Viability Assay	Homo sapiens	1	ALA4739714	cell-based format	Patent Bioactivity Data
10.	ALA4828797	F	Antiproliferative activity against human TC71 cells assessed as reduction in cell viability	Homo sapiens	2	ALA4828703	cell-based format	Scientific Literature
11.	ALA4828798	B	Inhibition of CDK2/Cyclin A (unknown origin)	Homo sapiens	20	ALA4828703	protein complex format	Scientific Literature
12.	ALA4828799	B	Inhibition of CDK7/Cyclin H (unknown origin)	Homo sapiens	20	ALA4828703	protein complex format	Scientific Literature
13.	ALA4828800	B	Inhibition of CDK9/Cyclin T1 (unknown origin)	Homo sapiens	20	ALA4828703	protein complex format	Scientific Literature
14.	ALA4828801	B	Inhibition of human recombinant CDK12/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzyme for 5 mins followed by substrate addition for 15 mins in presence of [gamma 32P-ATP] by radioactive kinase assay	Homo sapiens	20	ALA4828703	protein complex format	Scientific Literature
15.	ALA4828802	B	Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzyme for 5 mins followed by substrate addition for 15 mins in presence of [gamma 32P-ATP] by radioactive kinase assay	Homo sapiens	20	ALA4828703	protein complex format	Scientific Literature
16.	ALA4828803	A	Metabolic stability in mouse liver microsomes assessed as half life	Mus musculus	7	ALA4828703	microsome format	Scientific Literature
17.	ALA4828804	B	Binding affinity to CDK12 in CDK12/CyclinK complex (unknown origin) assessed as increase in CDK12 mass at 10-fold excess concentration incubated for 1 hr by LC-MS analysis	Homo sapiens	1	ALA4828703	single protein format	Scientific Literature
18.	ALA4828805	B	Inhibition of CDK12/13 in human jurkat cells assessed as reduction in RNA polymerase 2 CTD phosphorylation at Ser2 residue at 0.5 uM measured after 6 hrs by immunoblotting analysis	Homo sapiens	1	ALA4828703	cell-based format	Scientific Literature
19.	ALA4828806	B	Inhibition of CDK12/13 in human jurkat cells assessed as reduction in RNA polymerase 2 CTD phosphorylation at Ser2 residue at 1 uM measured after 6 hrs by immunoblotting analysis	Homo sapiens	2	ALA4828703	cell-based format	Scientific Literature
20.	ALA4828807	B	Inhibition of CDK12/13 in human Jurkat cells assessed as BRCA1 gene expression at 0.5 to 1 uM incubated for 4 hrs by RT-qPCR analysis	Homo sapiens	1	ALA4828703	cell-based format	Scientific Literature