# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4686519 | B | Inhibition of human cathepsin X expressed in Pichia pastoris assessed as residual activity at 50 uM using Abz-FEK(Dnp)-OH as substrate incubated for 30 to 45 mins by fluorescence assay relative to control | Homo sapiens | 42 | ALA4680241 | assay format | Scientific Literature | |
2. | ALA4686520 | B | Inhibition of human cathepsin X expressed in Pichia pastoris assessed as residual activity using Abz-FEK(Dnp)-OH as substrate incubated for 30 to 45 mins by fluorescence assay | Homo sapiens | 6 | ALA4680241 | assay format | Scientific Literature | |
3. | ALA4686521 | B | Inhibition of human cathepsin B expressed in Escherichia coli at 100 uM using Abz-GIVRAK(Dnp)-OH as substrate by fluorescence assay relative to control | Homo sapiens | 1 | ALA4680241 | assay format | Scientific Literature | |
4. | ALA4686522 | B | Inhibition of human cathepsin L expressed in Escherichia coli at 100 uM using Z-FR-AMC as substrate by fluorescence assay relative to control | Homo sapiens | 1 | ALA4680241 | assay format | Scientific Literature | |
5. | ALA4686523 | B | Inhibition of human cathepsin S expressed in Pichia pastoris at 100 uM using Z-VVR-AMC as substrate by fluorescence assay relative to control | Homo sapiens | 1 | ALA4680241 | assay format | Scientific Literature | |
6. | ALA4686524 | B | Inhibition of human cathepsin S expressed in Pichia pastoris using Z-VVR-AMC as substrate by fluorescence assay | Homo sapiens | 1 | ALA4680241 | assay format | Scientific Literature | |
7. | ALA4686526 | F | Cytotoxicity against human PC-3 cells assessed as reduction in cell viability at 20 uM after 24 to 48 hrs by MTS assay | Homo sapiens | 6 | ALA4680241 | cell-based format | Scientific Literature | |
8. | ALA4686527 | F | Antimigratory activity against human PC-3 cells at 10 uM up to 72 hrs by by xCELLigence based RTCA analysis relative to control | Homo sapiens | 1 | ALA4680241 | cell-based format | Scientific Literature |