# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4712753 | B | Allosteric activation of recombinant human full-length ALDH2 (18 to 517 residues) expressed in Escherichia coli at 100 uM using acetaldehyde as substrate measured after 3 hrs in presence of NAD+ by fluorescence assay relative to Alda-1 | Homo sapiens | 33 | assay format | Scientific Literature | ||
2. | ALA4712754 | B | Allosteric activation of recombinant human full-length ALDH2 (18 to 517 residues) expressed in Escherichia coli using acetaldehyde as substrate measured after 3 hrs in presence of NAD+ by fluorescence assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
3. | ALA4712755 | F | Protection against middle cerebral artery occlusion-induced Sprague-Dawley rat model of ischemic stroke-like event assessed as reduction in brain infarct size at 64 ug, icv pretreated for 5 mins followed by MCAO surgery for 2 hrs and subsequent reperfusion for 24 hrs by TCC staining based assay relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature |