# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4729127 | Binding | Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis | Mus musculus | 30 | ALA4725358 | cell-based format | Scientific Literature | |
2. | ALA4729128 | Binding | Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis relative to control | Mus musculus | 30 | ALA4725358 | cell-based format | Scientific Literature | |
3. | ALA4729129 | Binding | Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis relative to positive control | Mus musculus | 30 | ALA4725358 | cell-based format | Scientific Literature | |
4. | ALA4729130 | Binding | Agonist activity at mouse P2Y10 expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis | Mus musculus | 30 | ALA4725358 | cell-based format | Scientific Literature | |
5. | ALA4729131 | Binding | Agonist activity at mouse P2Y10 expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis relative to control | Mus musculus | 30 | ALA4725358 | cell-based format | Scientific Literature | |
6. | ALA4729132 | Binding | Agonist activity at mouse P2Y10 expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis relative to positive control | Mus musculus | 30 | ALA4725358 | cell-based format | Scientific Literature | |
7. | ALA4729133 | Functional | Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with Galphaq/i1 assessed as increase in calcium influx by calcium 5 dye based FLIPR assay | Mus musculus | 2 | ALA4725358 | cell-based format | Scientific Literature |