| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4733345 | B | Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate incubated for 30 mins by microplate reader assay | Homo sapiens | 27 | single protein format | Scientific Literature | ||
| 2. | ALA4733346 | B | Inhibition of MAGL in human U937 cells assessed as reduction in [3H]glycerol formation using [1,2,3-3H]2-OG as substrate incubated for 15 mins by liquid scintillation spectroscopy | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4733347 | A | Displacement of [3H]CP55940 from human CB1 receptor at 10 uM incubated for 90 mins by radioligand binding assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 4. | ALA4733348 | B | Displacement of [3H]CP55940 from human CB2 receptor at 10 uM incubated for 90 mins by radioligand binding assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 5. | ALA4733349 | B | Inhibition of human ABHD6 expressed in HEK293 cells using [3H]2-OG as substrate preincubated for 30 mins followed by substrate addition and measured after 5 mins by liquid scintillation spectroscopy | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA4733350 | B | Inhibition of human ABHD12 expressed in HEK293 cells using [3H]2-OG as substrate preincubated for 30 mins followed by substrate addition and measured after 5 mins by liquid scintillation spectroscopy | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4733351 | B | Inhibition of FAAH in human U937 cells assessed as reduction in [3H]ethanolamine formation using [ethanolamine-1-3H]AEA as substrate incubated for 15 mins by liquid scintillation spectroscopy | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA4733352 | B | Inhibition of MAGL in mouse brain membrane at 10 uM preincubated for 25 mins followed by TAMRA-FP labeling addition and measured after 5 mins by competitive ABPP based analysis | Mus musculus | 4 | cell membrane format | Scientific Literature | ||
| 9. | ALA4733353 | B | Inhibition of FAAH in mouse brain membrane up to 30 uM preincubated for 25 mins followed by TAMRA-FP labeling addition and measured after 5 mins by competitive ABPP based analysis | Mus musculus | 4 | cell membrane format | Scientific Literature | ||
| 10. | ALA4733354 | B | Inhibition of ABHD6 in mouse brain membrane up to 30 uM preincubated for 25 mins followed by TAMRA-FP labeling addition and measured after 5 mins by competitive ABPP based analysis | Mus musculus | 4 | cell membrane format | Scientific Literature | ||
| 11. | ALA4733355 | F | Antiproliferative activity against human HCT116 cells as reduction in cell growth measured after 96 hrs by Celltiter-glo luminescent assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 12. | ALA4733356 | F | Antiproliferative activity against human MDA-MB-231 cells as reduction in cell growth measured after 96 hrs by Celltiter-glo luminescent assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 13. | ALA4733357 | F | Antiproliferative activity against human CAOV3 cells as reduction in cell growth measured after 96 hrs by Celltiter-glo luminescent assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 14. | ALA4733358 | F | Antiproliferative activity against human OVCAR3 cells as reduction in cell growth measured after 96 hrs by Celltiter-glo luminescent assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 15. | ALA4733359 | F | Antiproliferative activity against human SKOV3 cells as reduction in cell growth measured after 96 hrs by Celltiter-glo luminescent assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 16. | ALA4733360 | F | Cytotoxicity against cancer-derived human organoids in HGSOC patient assessed as reduction in cell viability up to 100 uM measured after 96 hrs by Celltiter-glo luminescent assay | Homo sapiens | 5 | tissue-based format | Scientific Literature | ||
| 17. | ALA4733361 | F | Antiproliferative activity against human PDAC-3 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 18. | ALA4733362 | B | Reversible inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate preincubated with enzyme for 0 to 60 mins followed by substrate addition by microplate reader assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 19. | ALA4733363 | B | Reversible inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate at 2 uM preincubated with enzyme for 60 mins followed by 40X dilution and 15 mins later incubated with substrate by microplate reader assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 20. | ALA4733364 | B | Competitive inhibition of human recombinant MAGL using varying concentration of 4-nitrophenylacetate as substrate incubated for 30 mins by microplate reader assay | Homo sapiens | 4 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!