# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4717443 | ADME | Inhibition of human liver microsomes CYP2C9 using diclofenac as substrate by MUX-MS/MS analysis | Homo sapiens | 14 | ALA4715723 | microsome format | Scientific Literature | |
2. | ALA4717444 | ADME | Inhibition of human liver microsomes CYP2D6 using dextromethorphan as substrate by MUX-MS/MS analysis | Homo sapiens | 14 | ALA4715723 | microsome format | Scientific Literature | |
3. | ALA4717445 | ADME | Inhibition of human liver microsomes CYP3A4 using testosterone as substrate by MUX-MS/MS analysis | Homo sapiens | 14 | ALA4715723 | microsome format | Scientific Literature | |
4. | ALA4717446 | Binding | Inhibition of human ERG expressed in HEK293 cells assessed as reduction in S35-MK-0499 binding | Homo sapiens | 14 | ALA4715723 | cell-based format | Scientific Literature | |
5. | ALA4717447 | Binding | Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay | Homo sapiens | 47 | ALA4715723 | cell-based format | Scientific Literature | |
6. | ALA4717448 | Binding | Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay | Mus musculus | 32 | ALA4715723 | cell-based format | Scientific Literature | |
7. | ALA4717449 | ADME | Clearance in rat at 2 mg/kg, po or 1 mg/kg, iv | Rattus norvegicus | 7 | ALA4715723 | organism-based format | Scientific Literature | |
8. | ALA4717450 | ADME | Half life in rat at 2 mg/kg, po or 1 mg/kg, iv | Rattus norvegicus | 7 | ALA4715723 | organism-based format | Scientific Literature | |
9. | ALA4717451 | ADME | Volume of distribution at steady state in rat at 2 mg/kg, po or 1 mg/kg, iv | Rattus norvegicus | 7 | ALA4715723 | organism-based format | Scientific Literature | |
10. | ALA4717452 | ADME | Oral bioavailability in rat at 2 mg/kg | Rattus norvegicus | 6 | ALA4715723 | organism-based format | Scientific Literature | |
11. | ALA4717453 | ADME | Protein binding in rat plasma assessed as unbound fraction | Rattus norvegicus | 7 | ALA4715723 | cell-free format | Scientific Literature | |
12. | ALA4717454 | Physicochemical | Aqueous solubility of compound at pH 2 | 2 | ALA4715723 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA4717455 | Physicochemical | Aqueous solubility of compound at pH 7 | 2 | ALA4715723 | small-molecule physicochemical format | Scientific Literature |