# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4731875 | B | Modulation of human utrophinA expressed in mouse H2K-mdx utrnA-luc cells assessed as upregulation of utrophin production after 24 hrs by luciferase reporter gene assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
2. | ALA4731876 | B | Inhibition of firefly luciferase activity using ATP as substrate preincubated followed by substrate addition and measured after 15 mins by firefly luciferase reporter gene assay | Photinus pyralis | 25 | assay format | Scientific Literature | ||
3. | ALA4731877 | P | Lipophilicity, log D of the compound at pH 7.4 | 25 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA4731878 | P | Kinetic aqueous solubility of the compound | 23 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA4731880 | A | Apparent permeability across apical to basolateral side in human Caco2 cells | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
6. | ALA4731881 | A | Apparent permeability across basolateral to apical side in human Caco2 cells | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
7. | ALA4731882 | A | Intrinsic clearance in mouse hepatocyte | Mus musculus | 25 | tissue-based format | Scientific Literature | ||
8. | ALA4731883 | A | Half life in mouse hepatocyte | Mus musculus | 25 | tissue-based format | Scientific Literature | ||
9. | ALA4731885 | A | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 40 hrs by cell titer glo assay | Homo sapiens | 6 | cell-based format | Scientific Literature |