| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4689078 | A | Cytotoxicity against mouse N2a cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA4689079 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as reduction in ATP-induced calcium influx at 5 uM incubated for 1 hr by Fura-2AM dye based spectrofluorometry relative to control | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA4689081 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as reduction in ATP-induced EtBr uptake by cells incubated for 1 hr by fluorescence based assay relative to control | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4689083 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as reduction in ATP-induced YO-PRO-1 uptake by cells at 10 uM incubated for 1 hr by fluorescence based assay relative to control | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 5. | ALA4689090 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as cytoprotective activity against ATP-induced cell death by measuring increase in cell viability at 0.1 to 5 uM incubated for 1 hr followed by ATP addition and measured after 48 hrs by MTT assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4689091 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as inhibition of ATP-induced ROS production at 1 uM incubated for 1 hr by using H2DCF-DA probe based fluorescence assay relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4689095 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as inhibition of ATP-induced NO production by measuring NO level at 1 uM incubated for 1 hr by using DAF-FM probe based fluorescence assay relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4689098 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as reduction in ATP-induced calcium influx at 5 uM incubated for 1 hr by Fluo-3AM dye based laser scanning microscopy | Mus musculus | 1 | cell-based format | Scientific Literature |
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