| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4684873 | Binding | Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELISA | Mus musculus | 18 | ALA4680187 | single protein format | Scientific Literature | |
| 2. | ALA4684874 | Binding | Antagonist activity at EphA2-Fc in human PC3 cells assessed as reduction in ephrin-A1-Fc stimulated EphA2 phosphorylation preincubated for 20 mins followed by ephrin-A1 stimulation and measured after 20 mins by ELISA | Homo sapiens | 5 | ALA4680187 | cell-based format | Scientific Literature | |
| 3. | ALA4684875 | ADME | Cytotoxicity against human PC3 cells after 2 hrs by LDH assay | Homo sapiens | 5 | ALA4680187 | cell-based format | Scientific Literature |
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