# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4727730 | Binding | Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as reduction in LPS-induced IL-1beta release | Mus musculus | 7 | ALA4725325 | cell-based format | Scientific Literature | |
2. | ALA4727731 | Binding | Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta release | Homo sapiens | 7 | ALA4725325 | cell-based format | Scientific Literature | |
3. | ALA4727732 | ADME | Cytotoxicity against mouse J774.A1 cells | Mus musculus | 7 | ALA4725325 | cell-based format | Scientific Literature | |
4. | ALA4727733 | ADME | Cytotoxicity against human HEK-293T cells | Homo sapiens | 7 | ALA4725325 | cell-based format | Scientific Literature | |
5. | ALA4727734 | Toxicity | Therapeutic index, ratio of IC50 for cytotoxicity against mouse J774.A1 cells to IC50 for antiinflammatory activity in mouse J774.A1 cells | Mus musculus | 7 | ALA4725325 | cell-based format | Scientific Literature |