# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4727603 | B | Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]-methyl-alpha -D-glucopyranoside accumulation | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
2. | ALA4727604 | B | Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]-methyl-alpha -D-glucopyranoside accumulation | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
3. | ALA4727607 | A | Stability of compound in human liver microsomes assessed as parent compound remaining at 1 uM measured at 10 mins in presence of NADPH | Homo sapiens | 11 | microsome format | Scientific Literature | ||
4. | ALA4727609 | A | Stability of compound in mouse liver microsomes assessed as parent compound remaining at 1 uM measured at 10 mins in presence of NADPH | Mus musculus | 11 | microsome format | Scientific Literature | ||
5. | ALA4727610 | A | Stability of compound in rat liver microsomes assessed as parent compound remaining at 1 uM measured at 10 mins in presence of NADPH | Rattus norvegicus | 11 | microsome format | Scientific Literature | ||
6. | ALA4727611 | A | Clearance in Sprague-Dawley rat at 2 mg/kg, iv or 10 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
7. | ALA4727612 | A | Volume of distribution at steady state in Sprague-Dawley rat at 2 mg/kg, iv or 10 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
8. | ALA4727613 | A | Half life in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
9. | ALA4727615 | A | Cmax in Sprague-Dawley rat at 2 mg/kg, iv or 10 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
10. | ALA4727616 | A | Tmax in Sprague-Dawley rat at 2 mg/kg, iv or 10 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
11. | ALA4727617 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg | Rattus norvegicus | 4 | organism-based format | Scientific Literature |