| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4719417 | F | Induction of cell death in human HepG2 cells assessed as increase in number of dead cells at 10 to 20 uM measured after 72 hrs | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 2. | ALA4719418 | F | Synergistic cell killing effect in human HepG2 cells assessed as combination index at 10 uM measured after 24 hrs in presence of doxorubicin | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 3. | ALA4719419 | F | Synergistic cell killing effect in human HepG2 cells assessed as combination index at 10 uM measured after 24 hrs in presence of 2 ug/ml mitomycin | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 4. | ALA4719420 | F | Synergistic cell killing effect in human Huh-7 cells assessed as combination index at 10 uM measured after 24 hrs in presence of doxorubicin | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 5. | ALA4719421 | F | Synergistic cell killing effect in human Hep3B cells assessed as combination index at 10 uM in presence of doxorubicin | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 6. | ALA4719422 | F | Induction of cell death in human Hep3B cells assessed as increase in number of dead cells at 10 to 20 uM measured after 24 hrs | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 7. | ALA4719423 | F | Decrease in cell expansion in human HepG2 cells at 10 to 20 uM measured after 48 to 72 hrs by Neubauer chamber method | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 8. | ALA4719424 | F | Decrease in cell expansion in human Huh-7 cells at 10 to 20 uM measured after 24 hrs by Neubauer chamber method | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 9. | ALA4719425 | B | Inhibition of human full length FUBP1 expressed in Escherichia coli BL21 DE3 assessed as reduction in FUBP1 interaction with FUSE BIK oligonucleotide at 100 uM incubated for 21 hrs by Alphascreen assay relative to DMSO | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 10. | ALA4719426 | B | Inhibition of human full length FUBP1 expressed in Escherichia coli BL21 DE3 assessed as reduction in FUBP1 interaction with FUSE p21 oligonucleotide at 100 uM incubated for 21 hrs by Alphascreen assay relative to DMSO | Homo sapiens | 4 | ALA4715785 | cell-based format | Scientific Literature | |
| 11. | ALA4719427 | B | Inhibition of full length 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized FUSE p21 oligonucleotide by measuring time taken for association at 100 uM incubated for 21 hrs by SPR analysis | Homo sapiens | 4 | ALA4715785 | cell-based format | Scientific Literature | |
| 12. | ALA4719428 | B | Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized FUSE p21 oligonucleotide by measuring time taken for dissociation at 100 uM incubated for 21 hrs by SPR analysis | Homo sapiens | 4 | ALA4715785 | cell-based format | Scientific Literature | |
| 13. | ALA4719429 | B | Inhibition of human full length FUBP1 expressed in Escherichia coli BL21 DE3 assessed as reduction in FUBP1 interaction with FUSE p21 oligonucleotide incubated for 21 hrs by Alphascreen assay | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 14. | ALA4719430 | B | Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized FUSE p21 oligonucleotide incubated for 21 hrs by SPR analysis | Homo sapiens | 32 | ALA4715785 | cell-based format | Scientific Literature | |
| 15. | ALA4719431 | B | Inhibition of FUBP1 in human Hep3B cells assessed as upregulation of p21 mRNA expression at 50 uM after 6 hrs by qRT-PCR analysis relative to control | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 16. | ALA4719432 | B | Inhibition of FUBP1 in human Hep3B cells assessed as upregulation of BIK mRNA expression at 50 uM after 6 hrs by qRT-PCR analysis relative to control | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 17. | ALA4719433 | B | Inhibition of FUBP1 in human Hep3B cells assessed as downregulation of CCND2 mRNA expression at 50 uM after 6 hrs by qRT-PCR analysis relative to control | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 18. | ALA4719434 | F | Decrease in cell expansion in human Hep3B cells at 10 to 20 uM measured after 48 to 72 hrs by Neubauer chamber method | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 19. | ALA4719435 | F | Cell cycle arrest in human Hep3B cells assessed as accumulation at sub-G1 phase at 10 uM measured after 24 hrs by propidium iodide and RNase A staining based Nicoletti assay (Rvb = 2.5 %) | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature | |
| 20. | ALA4719436 | F | Cell cycle arrest in human Hep3B cells assessed as accumulation at sub-G1 phase at 20 uM measured after 24 hrs by propidium iodide and RNase A staining based Nicoletti assay (Rvb = 2.5 %) | Homo sapiens | 1 | ALA4715785 | cell-based format | Scientific Literature |
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