| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4731317 | ADME | Displacement of fluorescent probe SLFb-2PEG-TAMRA from N-terminal 6His-SUMO-tagged human full length FKBP12 expressed in Escherichia coli BL21 (DE3) cells measured after 1 hr by fluorescence polarisation assay | Homo sapiens | 16 | ALA4725452 | cell-based format | Scientific Literature | |
| 2. | ALA4731318 | Binding | Binding affinity to N-terminal 6His-SUMO-tagged Plasmodium falciparum FKBP35 binding domain (FBD35) (Q5-A128) expressed in Escherichia coli BL21 (DE3) cells assessed as change in melting temperature at 40 uM by differential scanning colorimetric analysis | Plasmodium falciparum | 19 | ALA4725452 | cell-based format | Scientific Literature | |
| 3. | ALA4731319 | Binding | Displacement of fluorescent probe SLFb-2PEG-TAMRA from N-terminal 6His-SUMO-tagged Plasmodium falciparum FKBP35 binding domain (FBD35) (Q5-A128) expressed in Escherichia coli BL21 (DE3) cells measured after 1 hr by fluorescence polarisation assay | Plasmodium falciparum | 16 | ALA4725452 | cell-based format | Scientific Literature | |
| 4. | ALA4731320 | ADME | Binding affinity to N-terminal 6His-SUMO-tagged human full length FKBP12 expressed in Escherichia coli BL21 (DE3) cells assessed as change in melting temperature at 40 uM by differential scanning colorimetric analysis | Homo sapiens | 19 | ALA4725452 | cell-based format | Scientific Literature | |
| 5. | ALA4731327 | Binding | Covalent binding affinity to N-terminal 6His-SUMO-tagged Plasmodium falciparum FKBP35 binding domain (FBD35) (Q5-A128) expressed in Escherichia coli BL21 (DE3) cells assessed as reaction half-life for FKBP35 consumption at 2250 nM incubated for 24 hrs by LC-MS analysis | Plasmodium falciparum | 2 | ALA4725452 | cell-based format | Scientific Literature | |
| 6. | ALA4731331 | Binding | Displacement of fluorescent tracer Rap-Gly-BDP from nanoluciferse-tagged Plasmodium falciparum FKBP35 expressed in HEK293T cells at 0.001 to 100 uM incubated for 2 hrs by NanoBRET assay | Plasmodium falciparum | 7 | ALA4725452 | cell-based format | Scientific Literature | |
| 7. | ALA4731332 | ADME | Displacement of fluorescent tracer Rap-Gly-BDP from nanoluciferse-tagged human FKBP12 expressed in HEK293T cells at 0.001 to 100 uM incubated for 2 hrs by NanoBRET assay | Homo sapiens | 7 | ALA4725452 | cell-based format | Scientific Literature |
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