# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4706356 | Binding | Antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12-alpha induced response pre-incubated for 15 mins before CXCL12-alpha addition and measured after 24 hrs | Homo sapiens | 70 | ALA4699667 | cell-based format | Scientific Literature | |
2. | ALA4706357 | Binding | Inhibition of human ERG expressed in CHO cells at -40 mV holding potential by Q-patch clamp assay | Homo sapiens | 28 | ALA4699667 | cell-based format | Scientific Literature | |
3. | ALA4706362 | Physicochemical | Distribution coefficient, logD of compound at pH 7.4 by HPLC based miniaturized shake-flask method | 26 | ALA4699667 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4706363 | ADME | Intrinsic clearance in human liver microsomes at 1 uM in presence of NADPH regenerating system incubated up to 45 mins by LC/MS-MS analysis | Homo sapiens | 25 | ALA4699667 | microsome format | Scientific Literature | |
5. | ALA4706366 | ADME | Protein binding in human plasma by LC-MS/MS based equilibrium analysis | Homo sapiens | 24 | ALA4699667 | cell-free format | Scientific Literature | |
6. | ALA4706367 | Physicochemical | Dissociation constant, pKa of compound by potentiometric or spectroscopic titration analysis | 16 | ALA4699667 | small-molecule physicochemical format | Scientific Literature |