# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4731317 | ADME | Displacement of fluorescent probe SLFb-2PEG-TAMRA from N-terminal 6His-SUMO-tagged human full length FKBP12 expressed in Escherichia coli BL21 (DE3) cells measured after 1 hr by fluorescence polarisation assay | Homo sapiens | 16 | ALA4725452 | cell-based format | Scientific Literature | |
2. | ALA4731318 | Binding | Binding affinity to N-terminal 6His-SUMO-tagged Plasmodium falciparum FKBP35 binding domain (FBD35) (Q5-A128) expressed in Escherichia coli BL21 (DE3) cells assessed as change in melting temperature at 40 uM by differential scanning colorimetric analysis | Plasmodium falciparum | 19 | ALA4725452 | cell-based format | Scientific Literature | |
3. | ALA4731319 | Binding | Displacement of fluorescent probe SLFb-2PEG-TAMRA from N-terminal 6His-SUMO-tagged Plasmodium falciparum FKBP35 binding domain (FBD35) (Q5-A128) expressed in Escherichia coli BL21 (DE3) cells measured after 1 hr by fluorescence polarisation assay | Plasmodium falciparum | 16 | ALA4725452 | cell-based format | Scientific Literature | |
4. | ALA4731320 | ADME | Binding affinity to N-terminal 6His-SUMO-tagged human full length FKBP12 expressed in Escherichia coli BL21 (DE3) cells assessed as change in melting temperature at 40 uM by differential scanning colorimetric analysis | Homo sapiens | 19 | ALA4725452 | cell-based format | Scientific Literature | |
5. | ALA4731321 | Physicochemical | Aqueous solubility of compound in PBS at pH 7.4 | 7 | ALA4725452 | small-molecule physicochemical format | Scientific Literature |