# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4701818 | Functional | Antagonist activity at human NPBWR1 assessed as inhibition of agonist-induced cAMP accumulation by cAMP assay | Homo sapiens | 45 | ALA4699486 | assay format | Scientific Literature | |
2. | ALA4701819 | Functional | Antagonist activity at recombinant human GPR7 assessed as reduction in agonist-induced inhibition of forskolin induced cAMP accumulation by measuring saturable parallel rightward shifts in agonist dose response by Schild plot analysis | Homo sapiens | 1 | ALA4699486 | assay format | Scientific Literature | |
3. | ALA4701820 | Binding | Competitive orthosteric antagonist activity at human GPR7 expressed in CHO cell membranes assessed as increase in Koff rate kinetics of [125I]-labeled human NPW23 at 0 to 30 uM by real-time scintillation proximity binding assay | Homo sapiens | 1 | ALA4699486 | cell membrane format | Scientific Literature | |
4. | ALA4701821 | Functional | Agonist activity at recombinant human GPR7 assessed as inhibition of forskolin induced cAMP accumulation | Homo sapiens | 1 | ALA4699486 | assay format | Scientific Literature | |
5. | ALA5127362 | Binding | Negative allosteric modulation activity at NPBWR1 (unknown origin) | Homo sapiens | 2 | ALA5126516 | single protein format | Scientific Literature |