| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4737004 | B | Inhibition of GSTP1-1 (unknown origin) using reduced GSH and CDNB as substrate incubated for 10 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 22 | ALA4732174 | single protein format | Scientific Literature | |
| 2. | ALA4737005 | B | Inhibition of GSTM2-2 (unknown origin) using reduced GSH and CDNB as substrate incubated for 10 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 22 | ALA4732174 | single protein format | Scientific Literature | |
| 3. | ALA4737006 | B | Selectivity index, ratio of IC50 for GSTP1-1 (unknown origin) to IC50 for GSTM2-2 (unknown origin) | 22 | ALA4732174 | assay format | Scientific Literature | ||
| 4. | ALA4737007 | P | Water solubility of the compound measured by UV-Visible spectral analysis | 6 | ALA4732174 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA4737008 | B | Inhibition of GSTM1-1 (unknown origin) at 100 uM using reduced GSH and CDNB as substrate incubated for 10 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 1 | ALA4732174 | single protein format | Scientific Literature | |
| 6. | ALA4737009 | B | Inhibition of GSTO1-1 (unknown origin) at 100 uM using reduced GSH and CDNB as substrate incubated for 10 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 1 | ALA4732174 | single protein format | Scientific Literature | |
| 7. | ALA4737010 | B | Noncompetitive inhibition of GSTP1-1 (unknown origin) assessed as reduction in Vmax with unchanged Km at 5 to 10 uM using varying concentration of CDNB and 1 mM reduced GSH as substrate measured every 30 sec by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA4732174 | single protein format | Scientific Literature | |
| 8. | ALA4737011 | B | Noncompetitive inhibition of GSTP1-1 (unknown origin) assessed as reduction in Vmax with unchanged Km at 5 to 10 uM using varying concentration of GSH and 1 mM CDNB as substrate measured every 30 sec by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA4732174 | single protein format | Scientific Literature | |
| 9. | ALA4737012 | B | Time dependent inhibition of GSTP1-1 (unknown origin) assessed as Kinact at 0.1 to 5 uM using reduced GSH and CDNB as substrate by spectrophotometric method | Homo sapiens | 2 | ALA4732174 | single protein format | Scientific Literature | |
| 10. | ALA4737013 | B | Time dependent inhibition of GSTP1-1 (unknown origin) assessed as inhibition constant using reduced GSH and CDNB as substrate by spectrophotometric method | Homo sapiens | 2 | ALA4732174 | single protein format | Scientific Literature | |
| 11. | ALA4737014 | A | Cytotoxicity against HUVEC assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA4732174 | cell-based format | Scientific Literature | |
| 12. | ALA4737015 | A | Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA4732174 | cell-based format | Scientific Literature | |
| 13. | ALA4737016 | F | Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA4732174 | cell-based format | Scientific Literature | |
| 14. | ALA4737017 | F | Antiproliferative activity against human B16 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA4732174 | cell-based format | Scientific Literature | |
| 15. | ALA4737018 | F | Antiproliferative activity against human 143B cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA4732174 | cell-based format | Scientific Literature | |
| 16. | ALA4737019 | F | Antiproliferative activity against human HOS cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA4732174 | cell-based format | Scientific Literature | |
| 17. | ALA4737020 | F | Induction of cell cycle arrest in human 143B cells assessed as accumulation at G1 phase at 2.5 uM incubated for 48 hrs by propidium iodide staining based flow cytometry (Rvb = 66.62 %) | Homo sapiens | 1 | ALA4732174 | cell-based format | Scientific Literature | |
| 18. | ALA4737021 | F | Induction of cell cycle arrest in human 143B cells assessed as accumulation at S phase at 2.5 uM incubated for 48 hrs by propidium iodide staining based flow cytometry (Rvb = 32.03 %) | Homo sapiens | 1 | ALA4732174 | cell-based format | Scientific Literature | |
| 19. | ALA4737022 | F | Induction of cell cycle arrest in human 143B cells assessed as accumulation at G2 phase at 2.5 uM incubated for 48 hrs by propidium iodide staining based flow cytometry (Rvb = 1.35 %) | Homo sapiens | 1 | ALA4732174 | cell-based format | Scientific Literature | |
| 20. | ALA4737023 | F | Induction of cell cycle arrest in human 143B cells assessed as accumulation at G1 phase at 5 uM incubated for 48 hrs by propidium iodide staining based flow cytometry (Rvb = 66.62 %) | Homo sapiens | 1 | ALA4732174 | cell-based format | Scientific Literature |
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