| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4687834 | P | Kinetic solubility of the compound | 50 | small-molecule physicochemical format | Scientific Literature | |||
| 2. | ALA4687835 | A | Half life in mouse liver microsomes | Mus musculus | 40 | microsome format | Scientific Literature | ||
| 3. | ALA4687837 | B | Inhibition of PIM1 (unknown origin) by coupled kinetic assay | Homo sapiens | 52 | single protein format | Scientific Literature | ||
| 4. | ALA4687838 | B | Binding affinity to recombinant PIM1 (unknown origin) assessed as thermal stability by measuring temperature shift at 10 uM by differential scanning fluorimetry | Homo sapiens | 43 | single protein format | Scientific Literature | ||
| 5. | ALA4687839 | F | Antiproliferative activity against human MV4-11 cells | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
| 6. | ALA4687840 | F | Antiproliferative activity against human PC-3 cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4687841 | A | Inhibition of CYP1A (unknown origin) | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 8. | ALA4687842 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 9. | ALA4687843 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 10. | ALA4687844 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 11. | ALA4687845 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 12. | ALA4687846 | B | Inhibition of human ERG | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 13. | ALA4687847 | B | Inhibition of PIM in human MV4-11 cells assessed as reduction in phosphorylated 4EBP1 at Thr70 at 10 uM by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4687848 | F | Reduction in total 4EBP1 protein level in human MV4-11 cells at 10 uM by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4687849 | A | Efflux ratio of permeability in human Caco-2 cells | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 16. | ALA4687850 | A | Inhibition of human BTK assessed as residual activity at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA4687851 | A | Inhibition of human CDK1/cyclinB assessed as residual activity at 10 uM relative to control | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 18. | ALA4687852 | A | Inhibition of human CHK1 assessed as residual activity at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA4687853 | A | Inhibition of human CK2 assessed as residual activity at 10 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4687854 | A | Inhibition of human c-SRC assessed as residual activity at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!