# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4721894 | B | Modulator activity at GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells assessed as receptor transactivation by luciferase reporter gene assay | Homo sapiens | 18 | ALA4715826 | cell-based format | Scientific Literature | |
2. | ALA4721895 | A | Modulator activity at GAL4-fused human PPARalpha LBD (unknown origin) transfected in African green monkey CV1 cells assessed as receptor transactivation by luciferase reporter gene assay | Homo sapiens | 18 | ALA4715826 | cell-based format | Scientific Literature | |
3. | ALA4721896 | U | Selectivity index, ratio of EC50 for transactivation of GAL4-fused PPARalpha LBD (unknown origin) transfected in CV1 cells to EC50 for transactivation of GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells by luciferase reporter gene assay | Homo sapiens | 8 | ALA4715826 | cell-based format | Scientific Literature | |
4. | ALA4721897 | U | Selectivity index, ratio of EC50 for transactivation of GAL4-fused PPARgamma LBD (unknown origin) transfected in African green monkey CV1 cells to EC50 for transactivation of GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells by luciferase reporter gene assay | Homo sapiens | 8 | ALA4715826 | assay format | Scientific Literature | |
5. | ALA4721898 | A | Modulator activity at GAL4-fused human PPARgamma LBD (unknown origin) transfected in African green monkey CV1 cells assessed as receptor transactivation by luciferase reporter gene assay | Homo sapiens | 18 | ALA4715826 | cell-based format | Scientific Literature | |
6. | ALA4721899 | A | Half life in CD-1 mouse at 3 mg/kg, iv | Mus musculus | 16 | ALA4715826 | organism-based format | Scientific Literature | |
7. | ALA4721900 | A | Clearance in CD-1 mouse at 3 mg/kg, iv | Mus musculus | 16 | ALA4715826 | organism-based format | Scientific Literature | |
8. | ALA4721901 | A | AUC in CD-1 mouse at 3 mg/kg, iv | Mus musculus | 15 | ALA4715826 | organism-based format | Scientific Literature |