| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4669201 | B | Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production using all-trans-retinol as substrate pre-incubated with enzyme for 5 mins followed by further incubation with all-trans-retinol for 1 hr by normal phase HPLC analysis | Bos taurus | 3 | microsome format | Scientific Literature | ||
| 2. | ALA4669202 | F | Cytoprotective activity against human ARPE-19 cells assessed as reduction in all-trans-retinal induced cytotoxicity at 18 to 90 uM incubated for 6 hrs in presence of all-trans-retinal by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA5032820 | B | Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by normal phase HPLC analysis | Bos taurus | 18 | microsome format | Scientific Literature |
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