| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4737546 | B | Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells co- expressing GIRK channel by thallium mobilization assay | Rattus norvegicus | 16 | ALA4732192 | cell-based format | Scientific Literature | |
| 2. | ALA4737547 | B | Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells co- expressing GIRK channel by thallium mobilization assay relative to control | Rattus norvegicus | 15 | ALA4732192 | cell-based format | Scientific Literature | |
| 3. | ALA4737548 | A | Protein binding in rat plasma assessed as unbound fraction | Rattus norvegicus | 3 | ALA4732192 | cell-free format | Scientific Literature | |
| 4. | ALA4737549 | A | Protein binding in human plasma assessed as unbound fraction | Homo sapiens | 3 | ALA4732192 | cell-free format | Scientific Literature | |
| 5. | ALA4737550 | A | Protein binding in rat brain assessed as unbound fraction | Rattus norvegicus | 3 | ALA4732192 | tissue-based format | Scientific Literature | |
| 6. | ALA4737551 | A | Ratio of drug level in rat brain to plasma assessed as permeability coefficient at 0.2 mg/kg, iv | Rattus norvegicus | 2 | ALA4732192 | organism-based format | Scientific Literature | |
| 7. | ALA4737552 | A | Ratio of drug level in rat brain to plasma assessed as unbound permeability coefficient at 0.2 mg/kg, iv | Rattus norvegicus | 2 | ALA4732192 | organism-based format | Scientific Literature | |
| 8. | ALA4737553 | B | Displacement of [3H]quisqualate from mGluR1 from rat brain incubated for 60 mins by radiometric scintillation counting analysis | Rattus norvegicus | 1 | ALA4732192 | tissue-based format | Scientific Literature | |
| 9. | ALA4737554 | B | Displacement of [3H]LY341495 from full length human recombinant mGluR2 expressed in Chem-1 cells incubated for 60 mins by radiometric scintillation counting analysis | Homo sapiens | 1 | ALA4732192 | cell-based format | Scientific Literature | |
| 10. | ALA4737555 | B | Binding affinity to mGlu3 (unknown origin) | Homo sapiens | 1 | ALA4732192 | single protein format | Scientific Literature | |
| 11. | ALA4737556 | B | Binding affinity to mGlu5 (unknown origin) | Homo sapiens | 1 | ALA4732192 | single protein format | Scientific Literature | |
| 12. | ALA4737557 | B | Binding affinity to mGlu7 (unknown origin) | Homo sapiens | 1 | ALA4732192 | single protein format | Scientific Literature | |
| 13. | ALA4737558 | P | Kinetic solubility of compound | 2 | ALA4732192 | small-molecule physicochemical format | Scientific Literature | ||
| 14. | ALA4737559 | F | Reversal of haloperidol-induced catalepsy in Sprague-Dawley rat assessed as reduction in catalepsy at 3 mg/kg, ip and measured after 15 mins relative to untreated control | Rattus norvegicus | 1 | ALA4732192 | organism-based format | Scientific Literature | |
| 15. | ALA4737560 | F | Reversal of haloperidol-induced catalepsy in Sprague-Dawley rat assessed as reduction in catalepsy at 10 mg/kg, ip and measured after 15 mins relative to untreated control | Rattus norvegicus | 1 | ALA4732192 | organism-based format | Scientific Literature | |
| 16. | ALA4737561 | F | Reversal of haloperidol-induced catalepsy in Sprague-Dawley rat assessed as reduction in catalepsy at 30 mg/kg, ip and measured after 15 mins relative to untreated control | Rattus norvegicus | 1 | ALA4732192 | organism-based format | Scientific Literature | |
| 17. | ALA4737562 | F | Reversal of haloperidol-induced catalepsy in Sprague-Dawley rat assessed as latency time for withdrawl at 3 mg/kg, ip and measured after 15 mins (Rvb = 49.8 sec) | Rattus norvegicus | 1 | ALA4732192 | organism-based format | Scientific Literature | |
| 18. | ALA4737563 | F | Reversal of haloperidol-induced catalepsy in Sprague-Dawley rat assessed as latency time for withdrawl at 10 mg/kg, ip and measured after 15 mins (Rvb = 49.8 sec) | Rattus norvegicus | 1 | ALA4732192 | organism-based format | Scientific Literature | |
| 19. | ALA4737564 | F | Reversal of haloperidol-induced catalepsy in Sprague-Dawley rat assessed as latency time for withdrawl at 30 mg/kg, ip and measured after 15 mins (Rvb = 49.8 sec) | Rattus norvegicus | 1 | ALA4732192 | organism-based format | Scientific Literature | |
| 20. | ALA4737565 | F | Reversal of haloperidol-induced catalepsy in Sprague-Dawley rat administered intraperitoneally and measured after 15 mins | Rattus norvegicus | 1 | ALA4732192 | organism-based format | Scientific Literature |
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