# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4709468 | Binding | Inhibition of full length recombinant human N-terminal GST/His6-tagged PAK1 expressed in sf9 insect cells using tetra LRRWSLG as substrate preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay | Homo sapiens | 24 | ALA4706541 | cell-based format | Scientific Literature | |
2. | ALA4709469 | Binding | Inhibition of full length recombinant human N-terminal GST/His6-tagged PAK4 expressed in baculovirus infected sf9 insect cells using tetra LRRWSLG as substrate preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay | Homo sapiens | 6 | ALA4706541 | cell-based format | Scientific Literature | |
3. | ALA4709470 | Binding | Selectivity index ratio of IC50 for inhibition of human PAK4 to IC50 for human PAK1 | Homo sapiens | 6 | ALA4706541 | assay format | Scientific Literature | |
4. | ALA4709471 | Binding | Inhibition of human ERG | Homo sapiens | 7 | ALA4706541 | single protein format | Scientific Literature | |
5. | ALA4709472 | Binding | Inhibition of ABL1 (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
6. | ALA4709473 | Binding | Inhibition of AKT1 (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
7. | ALA4709474 | Binding | Inhibition of ALK (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
8. | ALA4709475 | Binding | Inhibition of AuroraA (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
9. | ALA4709476 | Binding | Inhibition of AXL (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
10. | ALA4709477 | Binding | Inhibition of BRAF (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
11. | ALA4709478 | Binding | Inhibition of BTK (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
12. | ALA4709479 | Binding | Inhibition of c-Kit (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
13. | ALA4709480 | Binding | Inhibition of CDK6/cyclin Dl (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | protein complex format | Scientific Literature | |
14. | ALA4709481 | Binding | Inhibition of EGFR (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
15. | ALA4709482 | Binding | Inhibition of EPHA1 (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
16. | ALA4709483 | Binding | Inhibition of ERK1 (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
17. | ALA4709484 | Binding | Inhibition of FLT3 (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
18. | ALA4709485 | Binding | Inhibition of MAP4K1 (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
19. | ALA4709486 | Binding | Inhibition of JAK1 (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature | |
20. | ALA4709487 | Binding | Inhibition of JNK1 (unknown origin) assessed as residual activity at 0.1 uM preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay relative to control | Homo sapiens | 1 | ALA4706541 | single protein format | Scientific Literature |