# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4731361 | F | Antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in human BE(2)-M17 cells pretreated with compound for 2 hrs followed by viral infection at MOI of 1.2 and measured after 7 hrs by immunostaining based confocal microscopic analysis | Venezuelan equine encephalitis virus | 11 | ALA4725463 | organism-based format | Scientific Literature | |
2. | ALA4731362 | T | Selectivity index, ratio of CC50 for cytotoxicity against mouse Neuro-2a cells to EC50 for antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in mouse Neuro-2a cells | 10 | ALA4725463 | cell-based format | Scientific Literature | ||
3. | ALA4731363 | F | Antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in mouse Neuro-2a cells pretreated with compound for 2 hrs followed by viral infection at MOI of 3.5 and measured after 7 hrs by immunostaining based confocal microscopic analysis | Venezuelan equine encephalitis virus | 11 | ALA4725463 | organism-based format | Scientific Literature | |
4. | ALA4731367 | B | Inhibition of recombinant VEEV nsP2 expressed in Escherichia coli BL21(DE3) using V12 as substrate after 24 hrs by discontinuous gel assay | Venezuelan equine encephalitis virus | 3 | ALA4725463 | assay format | Scientific Literature | |
5. | ALA4731368 | B | Inhibition of recombinant VEEV nsP2 expressed in Escherichia coli BL21(DE3) using V12 as substrate at 20 uM after 24 hrs by discontinuous gel assay relative to control | Venezuelan equine encephalitis virus | 3 | ALA4725463 | assay format | Scientific Literature | |
6. | ALA4731369 | B | Inhibition of recombinant VEEV nsP2 expressed in Escherichia coli BL21(DE3) using V12 as substrate at 0.9 uM after 24 hrs by discontinuous gel assay relative to control | Venezuelan equine encephalitis virus | 3 | ALA4725463 | assay format | Scientific Literature | |
7. | ALA4731372 | T | Selectivity index, ratio of CC50 for cytotoxicity against human BE(2)-M17 cells to EC50 for antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in human BE(2)-M17 cells | 10 | ALA4725463 | cell-based format | Scientific Literature | ||
8. | ALA4731378 | A | Cytotoxicity against human SK-N-BE(2)-M17 cells | Homo sapiens | 11 | ALA4725463 | cell-based format | Scientific Literature | |
9. | ALA4731379 | A | Cytotoxicity against mouse N2a cells | Mus musculus | 10 | ALA4725463 | cell-based format | Scientific Literature |