#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4689302	Functional	Agonist activity at human TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assay	Homo sapiens	12	ALA4680349	cell-based format	Scientific Literature
2.	ALA4689303	Functional	Agonist activity at mouse TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assay	Mus musculus	8	ALA4680349	cell-based format	Scientific Literature
3.	ALA4689304	Binding	Agonist activity at GST-tagged human FXR-LBD using biotinylated SRC-1 peptide as substrate at 10 uM by HTRF assay	Homo sapiens	2	ALA4680349	single protein format	Scientific Literature
4.	ALA4689305	Binding	Agonist activity at GST-tagged human FXR-LBD using biotinylated SRC-1 peptide as substrate at 20 uM by HTRF assay	Homo sapiens	2	ALA4680349	single protein format	Scientific Literature
5.	ALA4689306	Binding	Agonist activity at GST-tagged human FXR-LBD using biotinylated SRC-1 peptide as substrate at 50 uM by HTRF assay	Homo sapiens	2	ALA4680349	single protein format	Scientific Literature
6.	ALA4689307	ADME	Stability of the compound in human plasma assessed as parent compound remaining measured after 60 mins	Homo sapiens	2	ALA4680349	cell-free format	Scientific Literature
7.	ALA4689308	ADME	Stability of the compound in human plasma assessed as parent compound remaining measured after 120 mins	Homo sapiens	2	ALA4680349	cell-free format	Scientific Literature
8.	ALA4689309	Functional	Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 24 hrs by CCK8 assay	Homo sapiens	2	ALA4680349	cell-based format	Scientific Literature
9.	ALA4689310	Functional	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 24 hrs by CCK8 assay	Homo sapiens	2	ALA4680349	cell-based format	Scientific Literature
10.	ALA4689311	Functional	Antidiabetic activity against in C57BL/6J mouse assessed reduction in glucose AUC at 30 mg/kg, po pretreated for 60 mins followed by 2 g/kg glucose orally administered measured upto 120 mins by OGTT method relative to control	Mus musculus	2	ALA4680349	organism-based format	Scientific Literature
11.	ALA4689312	Functional	In vivo agonist activity at TGR5 in wild type C57BL/6J mouse assessed as induction of GLP-1 secretion at 30 mg/kg, po followed by 2 g/kg glucose orally administered measured after 5 mins by ELISA relative to control	Mus musculus	1	ALA4680349	organism-based format	Scientific Literature
12.	ALA4689313	Functional	Induction of GLP-1 secretion in TGR5 knock out C57BL/6J mouse assessed as serum GLP-1 level at 30 mg/kg, po followed by 2 g/kg glucose orally administered measured after 5 mins by ELISA relative to control	Mus musculus	1	ALA4680349	organism-based format	Scientific Literature