# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4705374 | Binding | Substrate activity at NQO1 in human HepG2 cells assessed as reduction in cell viability by WST-1 assay | Homo sapiens | 8 | ALA4699639 | cell-based format | Scientific Literature | |
2. | ALA4705377 | Functional | Suppression of rotenone-induced ATP depletion in human HepG2 cells assessed as increase in rescue of ATP level at 1 uM incubated for 2 hrs by Celltiter-Glo assay | Homo sapiens | 24 | ALA4699639 | cell-based format | Scientific Literature | |
3. | ALA4705378 | ADME | Cytotoxicity against human HepG2 cells assessed as cell reduction in cell viability at 25 uM incubated for 24 hrs by Celltiter-blue assay | Homo sapiens | 8 | ALA4699639 | cell-based format | Scientific Literature | |
4. | ALA4705379 | ADME | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability at 25 uM incubated for 24 hrs by Celltiter-blue assay relative to control | Homo sapiens | 28 | ALA4699639 | cell-based format | Scientific Literature | |
5. | ALA4705380 | ADME | Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability at 25 uM incubated for 24 hrs by Celltiter-blue assay | Homo sapiens | 31 | ALA4699639 | cell-based format | Scientific Literature | |
6. | ALA4705381 | ADME | Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability by WST-1 assay | Homo sapiens | 8 | ALA4699639 | cell-based format | Scientific Literature | |
7. | ALA4705382 | ADME | Cytotoxicity against human R8 cells assessed as reduction in cell viability by WST-1 assay | Homo sapiens | 8 | ALA4699639 | cell-based format | Scientific Literature | |
8. | ALA4705394 | Binding | Substrate activity at recombinant NQO1 (unknown origin) assessed as reduction in NADH level at 20 uM measured for 6 mins by microplate reader analysis | Homo sapiens | 6 | ALA4699639 | single protein format | Scientific Literature | |
9. | ALA4705395 | Binding | Substrate activity at NQO1 in human HepG2 cells assessed as reduction in cell viability in presence of NQO1 inhibitor dicoumarol by WST-1 assay | Homo sapiens | 8 | ALA4699639 | cell-based format | Scientific Literature | |
10. | ALA4705396 | Functional | Suppression of rotenone-induced ATP depletion in human HepG2 cells assessed as rescue of ATP level incubated for 2 hrs by Celltiter-Glo assay relative to control | Homo sapiens | 8 | ALA4699639 | cell-based format | Scientific Literature | |
11. | ALA4705397 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 25 uM incubated for 24 hrs by Celltiter-blue assay relative to control | Homo sapiens | 8 | ALA4699639 | cell-based format | Scientific Literature |