| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4672064 | F | Inhibition of muscle contraction in Swiss mouse isolated phrenic nerve hemidiaphragm muscle preparation assessed as reduction of 0.1 Hz stimulation-induced isometric twitch force incubated for 20 to 25 mins | Mus musculus | 4 | tissue-based format | Scientific Literature | ||
| 2. | ALA4672066 | B | Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as dissociation rate constant for inhibition of acetylcholine-induced channel current response at -70 mV holding potential by two-electrode voltage-clamp assay | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4672067 | B | Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response at -70 mV holding potential by two-electrode voltage-clamp assay | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4672068 | B | Inhibition of rat alpha3beta2 expressed in Xenopus laevis oocytes assessed as dissociation rate constant for inhibition of acetylcholine-induced channel current response at -70 mV holding potential by two-electrode voltage-clamp assay | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA4672069 | B | Inhibition of rat alpha3beta2 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response at -70 mV holding potential by two-electrode voltage-clamp assay | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA4672071 | A | Half life in human serum at 30 uM by LC-MS analysis | Homo sapiens | 4 | cell-free format | Scientific Literature | ||
| 7. | ALA4672072 | F | Induction of paralysis in adult Zebrafish assessed as induction of rapid flaccid skeletal muscle paralysis dosed via injection measured after 10 mins | Danio rerio | 4 | organism-based format | Scientific Literature | ||
| 8. | ALA4672073 | F | Induction of paralysis in Zebrafish assessed as inhibition of larvae movement movement at 100 uM added into the water and measured over 1 hr by larvae movement tracking analysis relative to control | Danio rerio | 4 | organism-based format | Scientific Literature | ||
| 9. | ALA4672091 | F | Reduction in fading of train-of four repetitive stimulation pattern in Swiss mouse isolated phrenic nerve hemidiaphragm muscle preparation at 20 nM | Mus musculus | 4 | tissue-based format | Scientific Literature |
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