| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4729628 | A | Terminal elimination half life in Sprague-Dawley rat at 3 mg/kg, iv measured after 0.03 to 72 hrs by LC-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA4729629 | B | Inhibition of human liver FBPase expressed in Escherichia coli BL21(DE3) using FBP as substrate in presence of PGI and G6PDH by spectrophotometric method | Homo sapiens | 91 | assay format | Scientific Literature | ||
| 3. | ALA4729630 | B | Inhibition of AMP deaminase in mouse hemolysates measured at 2 min interval for 1 hr by spectrophotometric method | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 4. | ALA4729631 | B | Inhibition of adenylate kinase (unknown origin) incubated for 5 mins by colorimetric method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA4729632 | B | Inhibition of recombinant human ADK measured at interval of 1 to 2 mins for 30 to 40 mins by spectrophotometric method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4729633 | B | Activation of mouse liver Glycogen phosphorylase | Mus musculus | 1 | assay format | Scientific Literature | ||
| 7. | ALA4729634 | B | Activation of rat liver phosphofructokinase | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 8. | ALA4729635 | B | Activation of human AMPKalpha1beta1gamma1 | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA4729636 | F | In vivo inhibition of gluconeogenesis in overnight-fasted obese ZDF rat assessed as reduction in blood glucose level at 50 mg/kg, po administered for 24 days followed by pyruvate challenge and measured after 30 mins on day 24 by oral pyruvate tolerance test | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4729637 | F | Antidiabetic activity in KKAy mouse assessed as reduction in fasting blood glucose level at 200 mg/kg, po administered for 26 days by glucose oxidase method relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4729638 | F | Antidiabetic activity in KKAy mouse assessed as reduction in postprandial blood glucose level at 200 mg/kg, po administered for 26 days by glucose oxidase method relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4729639 | F | Antidiabetic activity in KKAy mouse assessed as HbA1c level at 200 mg/kg, po administered for 30 days (Rvb = 6.2%) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4729640 | F | Antidiabetic activity in obese ZDF rat assessed as reduction in fasting blood glucose level at 50 mg/kg, po administered for 29 days by glucose oxidase method relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4729641 | F | Antidiabetic activity in obese ZDF rat assessed as reduction in postprandial blood glucose level at 50 mg/kg, po administered for 29 days by glucose oxidase method relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4729642 | F | Antidiabetic activity in obese ZDF rat assessed as HbA1c level at 50 mg/kg, po administered for 32 days (Rvb = 6.2%) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4729643 | F | In vivo inhibition of gluconeogenesis in overnight-fasted diabetic KKay mouse assessed as reduction in blood glucose level at 200 mg/kg, po administered for 34 days and measured on day 34 by oral pyruvate tolerance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4729644 | F | In vivo inhibition of gluconeogenesis in overnight-fasted diabetic KKay mouse assessed as reduction in blood glucose level at 200 mg/kg, po administered for 34 days followed by pyruvate challenge and measured after 30 mins on day 34 by oral pyruvate tolerance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4729645 | F | In vivo inhibition of gluconeogenesis in overnight-fasted obese ZDF rat assessed as reduction in blood glucose level at 50 mg/kg, po administered for 24 days and measured on day 24 by oral pyruvate tolerance test | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4729646 | F | In vivo inhibition of gluconeogenesis in overnight-fasted diabetic KKay mouse assessed as reduction in mean increase rate of blood glucose level at 200 mg/kg, po administered for 34 days followed by pyruvate challenge and measured after 30 mins on day 34 by oral pyruvate tolerance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4729647 | F | In vivo inhibition of gluconeogenesis in overnight-fasted obese ZDF rat assessed as reduction in mean increase rate of blood glucose level at 50 mg/kg, po administered for 24 days followed by pyruvate challenge and measured after 30 mins on day 24 by oral pyruvate tolerance test | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
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