| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4683967 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
| 2. | ALA4683968 | F | Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
| 3. | ALA4683969 | F | Selectivity index, ratio of IC50 for human MCF7 cells to IC50 for human HT-29 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay | Homo sapiens | 45 | assay format | Scientific Literature | ||
| 4. | ALA4684030 | A | Antiproliferative activity against human HEK293T cells assessed as reduction in cell viability after 72 hrs by alamar blue assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4684031 | B | Inhibition of bovine brain tubulin polymerization at 10 uM measured at 30 sec interval for 30 mins in presence of GTP by turbidimetry-based spectrophotometric method | Bos taurus | 5 | tissue-based format | Scientific Literature | ||
| 6. | ALA4684032 | B | Induction of microtubule depolymerization in human MCF7 cells at 10 to 100 nM after 16 hrs by immunofluorescence staining based confocal microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4684035 | B | Binding affinity to tubulin in human MCF7 cells assessed as inhibition of tubulin-EBI adduct formation preincubated for 2 hrs followed by EBI addition and measured after 1.5 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4684036 | F | Cell cycle arrest in human MCF7 cells assessed as accumulation at G2/M phase at 1 uM measured after 24 hrs by PI staining based flow cytometry analysis (Rvb = 24 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4684037 | F | Cell cycle arrest in human MCF7 cells assessed as accumulation at G2/M phase at 1 uM measured after 48 hrs by PI staining based flow cytometry analysis (Rvb = 24 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4684038 | F | Cell cycle arrest in human MCF7 cells assessed as accumulation at G2/M phase at 1 uM measured after 72 hrs by PI staining based flow cytometry analysis (Rvb = 24 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4684039 | F | Cell cycle arrest in human MCF7 cells assessed as accumulation at sub-G1 phase at 1 uM measured after 72 hrs by PI staining based flow cytometry analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4684040 | F | Cell cycle arrest in human MCF7 cells assessed as accumulation at G2/M phase at 1 uM by PI staining based flow cytometry analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4684041 | F | Cell cycle arrest in human HT-29 cells assessed as accumulation at G2/M phase at 1 uM measured after 24 hrs by PI staining based flow cytometry analysis (Rvb = 11 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4684042 | F | Cell cycle arrest in human HT-29 cells assessed as accumulation at G2/M phase at 1 uM measured after 48 hrs by PI staining based flow cytometry analysis (Rvb = 11 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4684043 | F | Cell cycle arrest in human HT-29 cells assessed as accumulation at G2/M phase at 1 uM measured after 72 hrs by PI staining based flow cytometry analysis (Rvb = 11 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4684044 | F | Cell cycle arrest in human HT-29 cells assessed as accumulation at sub-G1 phase at 1 uM measured after 48 hrs by PI staining based flow cytometry analysis (Rvb = 2.5 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4684045 | F | Cell cycle arrest in human HT-29 cells assessed as accumulation at G2/M phase at 1 uM measured by PI staining based flow cytometry analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4684046 | F | Induction of apoptosis in human MCF7 cells assessed as early apoptotic cells after 48 hrs by Annexin V-FITC and propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4684047 | F | Induction of apoptosis in human MCF7 cells assessed as late apoptotic cells after 48 hrs by Annexin V-FITC and propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4684048 | F | Induction of apoptosis in human MCF7 cells assessed as total apoptotic cells at 0.01 uM after 48 hrs by Annexin V-FITC and propidium iodide staining based flow cytometry (Rvb = 10 %) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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