| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4735221 | A | Effect on activated cytotoxic T cell population in mouse B16/F10 cells implanted humanized PD-1 C57BL/6J mouse assessed as CD3-positive cell population at 100 mg/kg, ig administered once daily via gavage for 14 days measured post-last dose by immunostaining based flow cytometry (Rvb = 20.3 %) | Mus musculus | 1 | ALA4732116 | organism-based format | Scientific Literature | |
| 2. | ALA4735222 | A | Effect on spleen helper T cell population in mouse B16/F10 cells implanted humanized PD-1 C57BL/6J mouse assessed as CD4-positive cell population at 100 mg/kg, ig administered once daily via gavage for 14 days measured post-last dose by immunostaining based flow cytometry (Rvb = 1.09 %) | Mus musculus | 1 | ALA4732116 | organism-based format | Scientific Literature | |
| 3. | ALA4735223 | F | Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay | Homo sapiens | 21 | ALA4732116 | cell-based format | Scientific Literature | |
| 4. | ALA4735224 | F | Antiproliferative activity against mouse MC38 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay | Mus musculus | 21 | ALA4732116 | cell-based format | Scientific Literature | |
| 5. | ALA4735225 | F | Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay | Homo sapiens | 21 | ALA4732116 | cell-based format | Scientific Literature | |
| 6. | ALA4735226 | F | Antiproliferative activity against mouse B16-F10 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay | Mus musculus | 21 | ALA4732116 | cell-based format | Scientific Literature | |
| 7. | ALA4735227 | F | Antiproliferative activity against human A549/PTX cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay | Homo sapiens | 21 | ALA4732116 | cell-based format | Scientific Literature | |
| 8. | ALA4735228 | A | Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay | Homo sapiens | 21 | ALA4732116 | cell-based format | Scientific Literature | |
| 9. | ALA4735229 | A | Cytotoxicity against human NCM460 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay | Homo sapiens | 21 | ALA4732116 | cell-based format | Scientific Literature | |
| 10. | ALA4735230 | B | Inhibition of pig brain tubulin polymerization by spectrophotometric method | Sus scrofa | 7 | ALA4732116 | tissue-based format | Scientific Literature | |
| 11. | ALA4735231 | B | Disruption of microtubule network in human HepG2 cells at 5 uM measured after 24 hrs by immunofluorescence assay | Homo sapiens | 1 | ALA4732116 | cell-based format | Scientific Literature | |
| 12. | ALA4735232 | F | Antimigratory activity against human HepG2 cells assessed as inhibition of cell migration at 0.1 to 5 uM measured after 24 hrs by scratch wound healing assay | Homo sapiens | 1 | ALA4732116 | cell-based format | Scientific Literature | |
| 13. | ALA4735233 | F | Inhibition of colony formation in human HepG2 cells incubated for 24 hrs followed by replacement with fresh medium and measured after 7 to 10 days by crystal violet staining based assay | Homo sapiens | 1 | ALA4732116 | cell-based format | Scientific Literature | |
| 14. | ALA4735234 | F | Cell cycle arrest in human HepG2 cells assessed as accumulation at G1 phase at 0.1 uM after 24 hrs by propidium staining based flow cytometry analysis (Rvb = 58.33%) | Homo sapiens | 1 | ALA4732116 | cell-based format | Scientific Literature | |
| 15. | ALA4735235 | F | Cell cycle arrest in human HepG2 cells assessed as accumulation at S phase at 0.1 uM after 24 hrs by propidium staining based flow cytometry analysis (Rvb = 28.74%) | Homo sapiens | 1 | ALA4732116 | cell-based format | Scientific Literature | |
| 16. | ALA4735236 | F | Cell cycle arrest in human HepG2 cells assessed as accumulation at G2 phase at 0.1 uM after 24 hrs by propidium staining based flow cytometry analysis (Rvb = 5.04%) | Homo sapiens | 1 | ALA4732116 | cell-based format | Scientific Literature | |
| 17. | ALA4735237 | F | Cell cycle arrest in human HepG2 cells assessed as accumulation at G1 phase at 1 uM after 24 hrs by propidium staining based flow cytometry analysis (Rvb = 58.33%) | Homo sapiens | 1 | ALA4732116 | cell-based format | Scientific Literature | |
| 18. | ALA4735238 | F | Cell cycle arrest in human HepG2 cells assessed as accumulation at S phase at 1 uM after 24 hrs by propidium staining based flow cytometry analysis (Rvb = 28.74%) | Homo sapiens | 1 | ALA4732116 | cell-based format | Scientific Literature | |
| 19. | ALA4735239 | F | Cell cycle arrest in human HepG2 cells assessed as accumulation at G2 phase at 1 uM after 24 hrs by propidium staining based flow cytometry analysis (Rvb = 5.04%) | Homo sapiens | 1 | ALA4732116 | cell-based format | Scientific Literature | |
| 20. | ALA4735240 | F | Cell cycle arrest in human HepG2 cells assessed as accumulation at G1 phase at 5 uM after 24 hrs by propidium staining based flow cytometry analysis (Rvb = 58.33%) | Homo sapiens | 1 | ALA4732116 | cell-based format | Scientific Literature |
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