# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4673536 | Functional | Antileishmanial activity against axenic amastigote stage of Leishmania mexicana (MNYC/BZ/62/M379) infected in mouse RAW264.7 cells assessed as induction of parasite killing incubated for 24 hrs by alamar blue dye based fluorescence analysis | Leishmania mexicana | 1 | ALA4673181 | organism-based format | Scientific Literature | |
2. | ALA4673537 | Toxicity | Selectivity index, ratio of ED50 for mouse RAW264.7 cells to ED50 for antileishmanial activity against axenic amastigote stage of Leishmania mexicana (MNYC/BZ/62/M379) | 12 | ALA4673181 | assay format | Scientific Literature | ||
3. | ALA4673538 | ADME | Cytotoxicity against mouse RAW264.7 cells assessed as induction of cell killing incubated for 24 hrs by alamar blue dye based fluorescence analysis | Mus musculus | 12 | ALA4673181 | cell-based format | Scientific Literature | |
4. | ALA4673539 | Functional | Antileishmanial activity against axenic amastigote stage of Leishmania mexicana (MNYC/BZ/62/M379) assessed as induction of parasite killing incubated for 24 hrs by alamar blue dye based fluorescence analysis | Leishmania mexicana | 57 | ALA4673181 | organism-based format | Scientific Literature | |
5. | ALA4673540 | Functional | Antileishmanial activity against axenic amastigote stage of Leishmania mexicana (MNYC/BZ/62/M379) assessed as inhibition of parasite proliferation at 50 uM incubated for 24 hrs by alamar blue dye based fluorescence analysis | Leishmania mexicana | 57 | ALA4673181 | organism-based format | Scientific Literature |