# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4708299 | Toxicity | Hepatotoxicity in primary human hepatocytes assessed as increase in lactate dehydrogenase release at 500 to 1000 uM measured after 3 to 12 hrs by fluorescence based analysis | Homo sapiens | 20 | ALA4706503 | cell-based format | Scientific Literature | |
2. | ALA4708300 | Toxicity | Hepatotoxicity in primary human hepatocytes assessed as decrease in GSH level at 500 to 1000 uM measured after 3 to 12 hrs by Thiol tracker violet dye based fluorescence analysis | Homo sapiens | 20 | ALA4706503 | cell-based format | Scientific Literature | |
3. | ALA4708309 | Toxicity | Hepatotoxicity in CD1 mouse assessed as increase in serum alanine aminotransferase level at 600 mg/kg, po measured after 12 hrs | Mus musculus | 14 | ALA4706503 | organism-based format | Scientific Literature | |
4. | ALA4708310 | Toxicity | Hepatotoxicity in CD1 mouse assessed as increase in serum aspartate aminotransferase level at 600 mg/kg, po measured after 12 hrs | Mus musculus | 14 | ALA4706503 | organism-based format | Scientific Literature | |
5. | ALA4708311 | Toxicity | Hepatotoxicity in CD1 mouse assessed as increase in serum alkaline phosphatase level at 600 mg/kg, po measured after 12 hrs | Mus musculus | 14 | ALA4706503 | organism-based format | Scientific Literature | |
6. | ALA4708312 | Toxicity | Renal toxicity in CD1 mouse assessed as increase in serum creatinine level at 600 mg/kg, po measured after 12 hrs | Mus musculus | 14 | ALA4706503 | organism-based format | Scientific Literature |