# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4685225 | Binding | Inhibition of human full-length recombinant His-tagged PI3K p110delta/p85alpha expressed in baculovirus expression system using PIP2 as substrate measured after 2 hrs by ADP-Glo luminescence assay | Homo sapiens | 17 | ALA4680196 | assay format | Scientific Literature | |
2. | ALA4685226 | Functional | Antiproliferative activity against human SU-DHL-6 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 13 | ALA4680196 | cell-based format | Scientific Literature | |
3. | ALA4685227 | Binding | Inhibition of human full-length recombinant N-terminal His-tagged PI3K p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substrate measured after 2 hrs by ADP-Glo luminescence assay | Homo sapiens | 2 | ALA4680196 | assay format | Scientific Literature | |
4. | ALA4685228 | Binding | Inhibition of human full-length recombinant His-tagged PI3K p110beta/p85beta expressed in baculovirus expression system using PIP2 as substrate measured after 2 hrs by ADP-Glo luminescence assay | Homo sapiens | 2 | ALA4680196 | assay format | Scientific Literature | |
5. | ALA4685229 | Binding | Inhibition of recombinant human full-length His-tagged p110gamma expressed in baculovirus expression system using PIP2 as substrate measured after 2 hrs by ADP-glo assay | Homo sapiens | 2 | ALA4680196 | assay format | Scientific Literature | |
6. | ALA4685230 | Binding | Selectivity ratio of IC50 for inhibition of human full-length recombinant N-terminal His-tagged PI3K p110alpha/p85alpha expressed in baculovirus expression system to IC50 for inhibition of human full-length recombinant His-tagged PI3K p110delta/p85alpha expressed in baculovirus expression system | Homo sapiens | 2 | ALA4680196 | assay format | Scientific Literature | |
7. | ALA4685231 | Binding | Selectivity ratio of IC50 for inhibition of human full-length recombinant His-tagged PI3K p110beta/p85beta expressed in baculovirus expression system to IC50 for inhibition of human full-length recombinant His-tagged PI3K p110delta/p85alpha expressed in baculovirus expression system | Homo sapiens | 2 | ALA4680196 | assay format | Scientific Literature | |
8. | ALA4685232 | Binding | Selectivity ratio of IC50 for inhibition of recombinant human full-length His-tagged p110gamma expressed in baculovirus expression system to IC50 for inhibition of human full-length recombinant His-tagged PI3K p110delta/p85alpha expressed in baculovirus expression system | Homo sapiens | 2 | ALA4680196 | assay format | Scientific Literature | |
9. | ALA5151502 | Binding | Inhibition of PI3Kdelta (unknown origin) at 0.1 uM using phosphatidylinositol as substrate incubated for 30 mins in presence of ATP by HTRF based assay relative to control | Homo sapiens | 26 | ALA5149992 | single protein format | Scientific Literature | |
10. | ALA5151503 | Binding | Inhibition of PI3Kdelta (unknown origin) at 0.01 uM using phosphatidylinositol as substrate incubated for 30 mins in presence of ATP by HTRF based assay relative to control | Homo sapiens | 26 | ALA5149992 | single protein format | Scientific Literature |