| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4685674 | B | Displacement of fluormone-AL green from GST-tagged androgen receptor LBD (unknown origin) at 10 uM measured after 4 hrs by fluorescence polarization assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 2. | ALA4685676 | B | Antagonist activity at androgen receptor in human LNCaP cells transfected with ARR2 PB-eGFP assessed as inhibition of DHT-induced transcriptional activity measured after 3 days by fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 3. | ALA4685677 | B | Inhibition of prostate specific antigen in human LNCaP cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4685678 | F | Effect on prostate specific antigen mRNA expression in human LNCaP cells at 0.1 to 10 uM measured after 48 hrs by SYBR green dye based qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4685679 | B | Antagonist activity at androgen receptor in human LNCaP cells assessed as reduction in DHT-induced TMPRSS2 mRNA expression after 48 hrs by SYBR green dye based qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4685680 | A | Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability at 50 uM after 24 hrs by MTT assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4685681 | B | Antagonist activity at androgen receptor in human LNCaP cells assessed as inhibition of DHT-induced receptor translocation at 10 uM preincubated for 12 hrs followed by DHT addition and measured after 90 mins by immunofluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4685682 | F | Antiproliferative activity against human LNCaP cells assessed as reduction in cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4685683 | F | Antiproliferative activity against human PC-3 cells assessed as reduction in cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4685684 | F | Antiproliferative activity against human DU-145 cells assessed as reduction in cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4685685 | F | Antiproliferative activity against human LNCaP C4-2 cells assessed as reduction in cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature |
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