# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4701487 | Binding | Inhibition of SYK (unknown origin) | Homo sapiens | 25 | ALA4699472 | single protein format | Scientific Literature | |
2. | ALA4701488 | Physicochemical | Lipophilicity, logD of compound in buffer:octanol (100:1) at pH 7.4 by shake flask method | 21 | ALA4699472 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4701489 | ADME | Intrinsic clearance in rat hepatocytes measured per million cells | Rattus norvegicus | 21 | ALA4699472 | cell-based format | Scientific Literature | |
4. | ALA4701490 | ADME | Intrinsic clearance in human liver microsomes | Homo sapiens | 21 | ALA4699472 | microsome format | Scientific Literature | |
5. | ALA4701491 | ADME | Apparent intrinsic permeability across apical to basolateral side in human Caco2 cells at apical: basolateral pH of 6.5:7.4 in presence of efflux inhibitors | Homo sapiens | 9 | ALA4699472 | cell-based format | Scientific Literature | |
6. | ALA4701492 | ADME | Efflux ratio of permeability from apical to basolateral side over basolateral to apical side in human Caco2 cells at apical:basolateral pH of 7.4:7.4 | Homo sapiens | 18 | ALA4699472 | cell-based format | Scientific Literature | |
7. | ALA4701493 | Binding | Inhibition of human ERG assessed as tail current by plate-based planar patch clamp assay | Homo sapiens | 19 | ALA4699472 | assay format | Scientific Literature | |
8. | ALA4701494 | Functional | Growth inhibition of human SU-DHL-4 cells after 72 hrs | Homo sapiens | 16 | ALA4699472 | cell-based format | Scientific Literature | |
9. | ALA4701495 | ADME | Clearance in Han Wistar rat at 2 umol/kg, po and 1 umol/kg, iv | Rattus norvegicus | 5 | ALA4699472 | organism-based format | Scientific Literature | |
10. | ALA4701496 | ADME | Volume of distribution at steady state in Han Wistar rat at 2 umol/kg, po and 1 umol/kg, iv | Rattus norvegicus | 5 | ALA4699472 | organism-based format | Scientific Literature | |
11. | ALA4701497 | ADME | Oral bioavailability in Han Wistar rat at 2 umol/kg | Rattus norvegicus | 5 | ALA4699472 | organism-based format | Scientific Literature | |
12. | ALA4701498 | ADME | Protein binding in Han Wistar rat plasma assessed as unbound fraction | Rattus norvegicus | 5 | ALA4699472 | cell-free format | Scientific Literature |