# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4711800 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv assessed as bacterial growth inhibition by MABA | Mycobacterium tuberculosis | 33 | organism-based format | Scientific Literature | ||
2. | ALA4711801 | F | Antitubercular activity against isoniazid/rifampicin multidrug-resistant Mycobacterium tuberculosis FJ05120 clinical isolates assessed as bacterial growth inhibition by MABA | Mycobacterium tuberculosis | 33 | organism-based format | Scientific Literature | ||
3. | ALA4711802 | F | Antitubercular activity against isoniazid/rifampicin/streptomycin/capreomycin/ofloxacin extensively drug-resistant Mycobacterium tuberculosis FJ05195 clinical isolates assessed as bacterial growth inhibition by MABA | Mycobacterium tuberculosis | 33 | organism-based format | Scientific Literature | ||
4. | ALA4711803 | A | Cytotoxicity against human HEK293 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
5. | ALA4711804 | T | Selectivity index, ratio of IC50 for human HEK293 cells to MIC for Mycobacterium tuberculosis | 4 | assay format | Scientific Literature | |||
6. | ALA4711805 | T | Acute toxicity in BALB/c mouse at 1000 mg/kg, po measured after 7 days | Mus musculus | 3 | organism-based format | Scientific Literature | ||
7. | ALA4711806 | A | Tmax in Sprague-Dawley rat at 40 mg/kg, po measured upto 8 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
8. | ALA4711807 | A | Cmax in Sprague-Dawley rat at 40 mg/kg, po measured upto 8 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
9. | ALA4711808 | A | AUC (0 to t) in Sprague-Dawley rat at 40 mg/kg, po measured upto 8 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
10. | ALA4711809 | A | Mean residence time in Sprague-Dawley rat at 40 mg/kg, po measured upto 8 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
11. | ALA4711810 | F | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 29213 assessed as bacterial growth inhibition incubated for 18 hrs by agar dilution method | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
12. | ALA4711811 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as bacterial growth inhibition incubated for 18 hrs by agar dilution method | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
13. | ALA4711812 | F | Antibacterial activity against methicillin-sensitive Staphylococcus epidermidis ATCC 12228 assessed as bacterial growth inhibition incubated for 18 hrs by agar dilution method | Staphylococcus epidermidis | 2 | organism-based format | Scientific Literature | ||
14. | ALA4711813 | F | Antibacterial activity against Vancomycin-susceptible Enterococcus faecalis ATCC 29212 assessed as bacterial growth inhibition incubated for 18 hrs by agar dilution method | Enterococcus faecalis | 2 | organism-based format | Scientific Literature | ||
15. | ALA4711814 | F | Antibacterial activity against vancomycin-resistant Enterococcus faecium ATCC 700221 assessed as bacterial growth inhibition incubated for 18 hrs by agar dilution method | Enterococcus faecium | 2 | organism-based format | Scientific Literature | ||
16. | ALA4711815 | F | Antibacterial activity against ESBLs negative Escherichia coli ATCC 25922 assessed as bacterial growth inhibition incubated for 18 hrs by agar dilution method | Escherichia coli | 2 | organism-based format | Scientific Literature | ||
17. | ALA4711816 | F | Antibacterial activity against ESBLs positive Klebsiella pneumoniae ATCC 700603 assessed as bacterial growth inhibition incubated for 18 hrs by agar dilution method | Klebsiella pneumoniae | 2 | organism-based format | Scientific Literature | ||
18. | ALA4711817 | F | Antibacterial activity against ESBLs negative Klebsiella pneumoniae 7 assessed as bacterial growth inhibition incubated for 18 hrs by agar dilution method | Klebsiella pneumoniae | 2 | organism-based format | Scientific Literature | ||
19. | ALA4711818 | F | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as bacterial growth inhibition incubated for 18 hrs by agar dilution method | Pseudomonas aeruginosa | 2 | organism-based format | Scientific Literature | ||
20. | ALA4711819 | F | Antibacterial activity against Acinetobacter calcoaceticus ATCC 19606 assessed as bacterial growth inhibition incubated for 18 hrs by agar dilution method | Acinetobacter calcoaceticus | 2 | organism-based format | Scientific Literature |