# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4739833 | Binding | Binding affinity to CDK12 in human Jurkat cells assessed as target occupancy level incubated for 2 hrs by measuring Bio-THZ531 bound protein level by spectrophotometry based plate based target engagement assay | Homo sapiens | 2 | ALA4739718 | cell-based format | Patent Bioactivity Data | |
2. | ALA4739834 | Binding | Binding affinity to CDK7 in human Jurkat cells assessed as target occupancy level incubated for 2 hrs by measuring Bio-THZ531 bound protein level by spectrophotometry based plate based target engagement assay | Homo sapiens | 2 | ALA4739718 | cell-based format | Patent Bioactivity Data | |
3. | ALA4739835 | Binding | Binding affinity to CDK12 (unknown origin) incubated for 1 hr by qPCR analysis | Homo sapiens | 13 | ALA4739718 | tissue-based format | Patent Bioactivity Data | |
4. | ALA4739836 | Binding | Inhibition of kinase tracer 236 binding to CDK13 (unknown origin) by FRET based Lantha screen Eu kinase binding assay | Homo sapiens | 14 | ALA4739718 | single protein format | Patent Bioactivity Data | |
5. | ALA4739837 | Binding | Inhibition of CDK7 (unknown origin) assessed as reduction in ATP-dependent phosphorylation of ULight-myelin basic protein substrate peptide incubated for 60 mins by LANCE TR-FRET assay | Homo sapiens | 14 | ALA4739718 | single protein format | Patent Bioactivity Data |