# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4670872 | Binding | Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability | Homo sapiens | 48 | ALA4665807 | cell-based format | Scientific Literature | |
2. | ALA4670873 | Binding | Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1 | Homo sapiens | 48 | ALA4665807 | cell-based format | Scientific Literature | |
3. | ALA4670874 | Binding | Selectivity ratio of EC50 for Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1 to EC50 for Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability | Homo sapiens | 16 | ALA4665807 | cell-based format | Scientific Literature | |
4. | ALA4670875 | Unassigned | Drug metabolism in PBS assessed as formation of N-(3-chloro-4-methoxyphenyl)-N-(2-oxo-2-(phenethylamino)-1-(thiophen-2-yl)ethyl)propiolamide at pH 7.4 | 1 | ALA4665807 | assay format | Scientific Literature | ||
5. | ALA4670876 | Unassigned | Drug metabolism in PBS assessed as thiol adduct formation at pH 7.4 | 1 | ALA4665807 | assay format | Scientific Literature |